DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment RIN3 and Amfr

DIOPT Version :9

Sequence 1:	NP_001190515.1	Gene:	RIN3 / 835219	AraportID:	AT5G51450	Length:	595	Species:	Arabidopsis thaliana
Sequence 2:	XP_038954087.1	Gene:	Amfr / 361367	RGDID:	1311551	Length:	643	Species:	Rattus norvegicus

Alignment Length:	555	Identity:	137/555 - (24%)
Similarity:	223/555 - (40%)	Gaps:	145/555 - (26%)

- Green bases have known domain annotations that are detailed below.

plant    51 ELLLSSHTTIALLASFVLNIYILLVLSLKTLFFGDLYAIETRKLVERLANYIIYKGTFLPFVV-P 114
            :.|||....:.:|.:....:.:|:...::.:.||.|...|.:.|.::..|:|.||..|:..|: .
  Rat    75 QYLLSDSLFVWVLVNTACCVLMLVAKLIQCIVFGPLRVSERQHLKDKFWNFIFYKFIFIFGVLNV 139

plant   115 RTVFQGVLWTIWLTVLCTLKMFQALARDRLDRLNASPSSTPWTYFRVYSALF-MVLSTDLCWIKL 178
            :||.:.|:|.:|...|..|.:...|.:||.:.|:.||::...::.||.|.|. |:||  .|.:.:
  Rat   140 QTVEEVVMWCLWFAGLVFLHLMVQLCKDRFEYLSFSPTTPMSSHGRVLSLLIAMLLS--CCGLAV 202

plant   179 SLMIYN-TVGSSVYLLLLFEPCGIAFETLQALLIHGFQLLDMWINHLAVKNSDCQRSKFYDSMTA 242
            ...:.. |.|......:..|...:...|...:|.:...|.|  :||
  Rat   203 VCCVTGYTHGMHTLAFMAAESLLVTVRTAHVILRYVIHLWD--LNH------------------- 246

plant   243 GSLLEWKGLLNRNLGFFLDMATLVMALGHYLHIWWLHGMAFHLVDAVLFLNIRALLSSILKRI-- 305
            ....|.||.......|.:::..|.:.|.|::|:.....:...:...|:|:.:|.|...:.:||
  Rat   247 EGTWEGKGTYVYYTDFVMELMLLSLDLMHHIHMLLFGNIWLSMASLVIFMQLRYLFHEVQRRIRR 311

plant   306 -KGYIKLRVALGALHAALLDATSEELRDYDDECAICREPMAKAKRLHCNHLFHLGCLRSWLDQGL 369
             |.|:::   :|.:.|....||:|||...:|:||||.:.|..|::|.|.||||..||||||:|..
  Rat   312 HKNYLRV---VGNMEARFAVATAEELAVNNDDCAICWDSMQAARKLPCGHLFHNSCLRSWLEQDT 373

plant   370 NEVYSCPTCRKPLFVGRTESEANPSRGEVSSDEHL-----ARQFERQNNSVHALTTGMFPTETPN 429
                ||||||..|.:..........:|| :.||:|     |....|.|...|
  Rat   374 ----SCPTCRMSLNIADGSRAREDHQGE-NLDENLVPVAAAEGRPRLNQHNH------------- 420

plant   430 FTESDPWRLAFLNGISSSHLFLMPYRNSEVDPSWLQTWSDQGVDVVGSSAGSRSVGLGQVQLMMR 494
            |...|..|:|                      |||.::|                    |::|
  Rat   421 FFHFDGSRIA----------------------SWLPSFS--------------------VEVM-- 441

plant   495 HLASVGEGSAQTTLDDASWGLWPMNPSQASTSSTYVPPGAGGRTGGLHLRTVSRAANNMASILAM 559
            |..::                  :..:|||.|                            .:.||
  Rat   442 HTTNI------------------LGITQASNS----------------------------QLNAM 460

plant   560 AETVREVLPHVPDEIIFQDLQRTNSVSVTVNNLLQ 594
            |..::|:.|.||..::.||||.|.||.:|.:|:|:
  Rat   461 AHQIQEMFPQVPYHLVLQDLQMTRSVEITTDNILE 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RIN3	NP_001190515.1	HRD1	57..>382	CDD:227568	92/330 (28%)
		RING	336..382	CDD:238093	25/45 (56%)
		CUE_RIN3_plant	556..593	CDD:270605	16/36 (44%)
Amfr	XP_038954087.1	HRD1	86..>382	CDD:227568	92/325 (28%)
		RING-H2_AMFR	339..382	CDD:319369	26/46 (57%)
		CUE_AMFR	458..498	CDD:270604	17/38 (45%)
		G2BR	575..600	CDD:375868
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I1864
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D897451at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_105132
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3836
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.870