Protein Alignment RIN3 and Amfr

DIOPT Version :9

• Sequence 1: NP_001190515.1
• Gene: RIN3 / 835219
• AraportID: AT5G51450
• Length: 595
• Species: Arabidopsis thaliana
• Sequence 2: NP_035917.2
• Gene: Amfr / 23802
• MGIID: 1345634
• Length: 639
• Species: Mus musculus
• Alignment Length: 576
• Identity: 142/576 - (24%)
• Similarity: 231/576 - (40%)
• Gaps: 153/576 - (26%)

plant    30 RLRADGIITKNISLGNSENTLELLLSSHTTIALLASFVLNIYILLVLSLKTLFFGDLYAIETRKL 94
            ||.|.|...::::        :.|||....:.:|.:....:.:|:...::.:.||.|...|.:.|
Mouse    58 RLTAGGPRARDVA--------QYLLSDSLFVWVLVNTACCVLMLVAKLIQCIVFGPLRVSERQHL 114

plant    95 VERLANYIIYKGTFLPFVV-PRTVFQGVLWTIWLTVLCTLKMFQALARDRLDRLNASPSSTPWTY 158
            .::..|:|.||..|:..|: .:||.:.|:|.:|...|..|.:...|.:||.:.|:.||::...::
Mouse   115 KDKFWNFIFYKFIFIFGVLNVQTVEEVVMWCLWFAGLVFLHLMVQLCKDRFEYLSFSPTTPMSSH 179

plant   159 FRVYSALF-MVLSTDLCWIKLSLMIYN-TVGSSVYLLLLFEPCGIAFETLQALLIHGFQLLDMWI 221
            .||.|.|. |:||  .|.:.:...:.. |.|......:..|...:...|...:|.:...|.|  :
Mouse   180 GRVLSLLIAMLLS--CCGLAVVCCVTGYTHGMHTLAFMAAESLLVTVRTAHVILRYVIHLWD--L 240

plant   222 NHLAVKNSDCQRSKFYDSMTAGSLLEWKGLLNRNLGFFLDMATLVMALGHYLHIWWLHGMAFHLV 286
            ||                   ....|.||.......|.:::|.|.:.|.|::|:.....:...:.
Mouse   241 NH-------------------EGTWEGKGTYVYYTDFVMELALLSLDLMHHIHMLLFGNIWLSMA 286

plant   287 DAVLFLNIRALLSSILKRI---KGYIKLRVALGALHAALLDATSEELRDYDDECAICREPMAKAK 348
            ..|:|:.:|.|...:.:||   |.|:::   :|.:.|....||.|||...:|:||||.:.|..|:
Mouse   287 SLVIFMQLRYLFHEVQRRIRRHKNYLRV---VGNMEARFAVATPEELAVNNDDCAICWDSMQAAR 348

plant   349 RLHCNHLFHLGCLRSWLDQGLNEVYSCPTCRKPLFVGRTESEANPSRGEVSSDEHL-----ARQF 408
            :|.|.||||..||||||:|..    ||||||..|.:..........:|| :.||:|     |...
Mouse   349 KLPCGHLFHNSCLRSWLEQDT----SCPTCRMSLNIADGSRAREDHQGE-NLDENLVPVAAAEGR 408

plant   409 ERQNNSVHALTTGMFPTETPNFTESDPWRLAFLNGISSSHLFLMPYRNSEVDPSWLQTWSDQGVD 473
            .|.|...|             |...|..|:|                      |||.::|
Mouse   409 PRLNQHNH-------------FFHFDGSRIA----------------------SWLPSFS----- 433

plant   474 VVGSSAGSRSVGLGQVQLMMRHLASVGEGSAQTTLDDASWGLWPMNPSQASTSSTYVPPGAGGRT 538
                           |::|  |..::                  :..:|||.|
Mouse   434 ---------------VEVM--HTTNI------------------LGITQASNS------------ 451

plant   539 GGLHLRTVSRAANNMASILAMAETVREVLPHVPDEIIFQDLQRTNSVSVTVNNLLQ 594
                            .:.|||..::|:.|.||..::.||||.|.||.:|.:|:|:
Mouse   452 ----------------QLNAMAHQIQEMFPQVPYHLVLQDLQMTRSVEITTDNILE 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RIN3	NP_001190515.1	HRD1	57..>382	CDD:227568	93/330 (28%)
		RING	336..382	CDD:238093	25/45 (56%)
		CUE_RIN3_plant	556..593	CDD:270605	16/36 (44%)
Amfr	NP_035917.2	HRD1	82..>378	CDD:227568	93/325 (29%)
		zf-RING_2	335..375	CDD:290367	24/43 (56%)
		CUE_AMFR	454..494	CDD:270604	17/38 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	500..531
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	594..620
		VCP/p97-interacting motif (VIM). /evidence=ECO:0000250|UniProtKB:Q9UKV5	618..636

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5243
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	180	1.000	Inparanoid score	I1819
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_105132
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3836
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.760