Protein Alignment KATNAL2 and SAP1

DIOPT Version :9

• Sequence 1: NP_001340828.1
• Gene: KATNAL2 / 83473
• HGNCID: 25387
• Length: 564
• Species: Homo sapiens
• Sequence 2: NP_010966.1
• Gene: SAP1 / 856771
• SGDID: S000000849
• Length: 897
• Species: Saccharomyces cerevisiae
• Alignment Length: 552
• Identity: 174/552 - (31%)
• Similarity: 266/552 - (48%)
• Gaps: 104/552 - (18%)

Human    48 TEARRKNLLILISHYLTQEGYIDTANALEQETKLG-------LRRFEVCDNIDLETILMEYESYY 105
            |.::.....|:.|:..:....:...|::.|:.|..       |...:|..|..|.|   ..:|:.
Yeast   411 TRSKSNTKPIIKSNASSPTSSLTVPNSVIQKPKTAAMAAKRVLNSKKVASNPALNT---TKKSHP 472

Human   106 FVKFQKYPKIVKKSSDTAENNLPQRSRGKTRRMMNDSCQN-LPKINQQRPRSKTTAGKTGDTKSL 169
            .:| .|..|:...||....:: |.|....::...:.:.|| .|..||....|||
Yeast   473 ILK-SKTAKVPNSSSKKTSSH-PSRPVSNSKPYSHGASQNKKPSKNQTTSMSKT----------- 524

Human   170 NKEHPNQEVVDNTRLESANFGLHISRIRKDSGEENAHPRRGQIIDFQGLLTDAIKGATSELALNT 234
            |::.|.|:.:.:.::|             |.|.|                 ||.:.|||   ||.
Yeast   525 NRKIPAQKKIGSPKIE-------------DVGTE-----------------DATEHATS---LNE 556

Human   235 FDHNPDPSERLLKPLSAFIGMNSEM--------RELAAVVSRDIYLHNPNIKWNDIIGLDAAKQL 291
            ....|:..:::|:.:     :..|:        |:.|..:..:|.:|...:.|:||.||::||..
Yeast   557 QREEPEIDKKVLREI-----LEDEIIDSLQGVDRQAAKQIFAEIVVHGDEVHWDDIAGLESAKYS 616

Human   292 VKEAVVYPIRYPQLFTGILSPWKGLLLYGPPGTGKTLLAKAVATECKTTFFNISASTIVSKWRGD 356
            :|||||||...|.||.|:..|.:|:||:||||||||:||:|||||..:|||:||||::.||:.|:
Yeast   617 LKEAVVYPFLRPDLFRGLREPVRGMLLFGPPGTGKTMLARAVATESHSTFFSISASSLTSKYLGE 681

Human   357 SEKLVRVLFELARYHAPSTIFLDELESVMSQRGTASGGEHEGSLRMKTELLVQMDGLARS----- 416
            ||||||.||.:|:..:||.||:||::|:|..|...:  |:|.|.|:|.|.|||...|:.:
Yeast   682 SEKLVRALFAIAKKLSPSIIFVDEIDSIMGSRNNEN--ENESSRRIKNEFLVQWSSLSSAAAGSN 744

Human   417 ------------ED--LVFVLAASNLPWELDCAMLRRLEKRILVDLPSREARQAMIYHWLPPVSK 467
                        ||  .|.||||:||||.:|.|..||..:|..:.||..:.|.......|
Yeast   745 KSNTNNSDTNGDEDDTRVLVLAATNLPWSIDEAARRRFVRRQYIPLPEDQTRHVQFKKLL----- 804

Human   468 SRALELHTELEYSVLSQETEGYSGSDIKLVCREAAMRPVRKIFDALENHQSESSDLPRIQLDIVT 532
            |......||.::..|.:.|||||||||..:.::|||.|:|.:.|.|...:.|       .:..:.
Yeast   805 SHQKHTLTESDFDELVKITEGYSGSDITSLAKDAAMGPLRDLGDKLLETERE-------MIRPIG 862

Human   533 TADFLDVLTHTKPS-AKNLAQRYSDWQREFES 563
            ..||.:.|.:.||| :::...:|..|..:|.|
Yeast   863 LVDFKNSLVYIKPSVSQDGLVKYEKWASQFGS 894

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KATNAL2	NP_001340828.1	LisH	51..81	CDD:128913	4/29 (14%)
		SpoVK	<264..559	CDD:223540	126/314 (40%)
SAP1	NP_010966.1	Herpes_BLLF1	<353..543	CDD:282904	32/160 (20%)
		SpoVK	<557..890	CDD:223540	131/351 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C159050827
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840