Protein Alignment SLC25A31 and DPCoAC

DIOPT Version :10

• Sequence 1: NP_112581.1
• Gene: SLC25A31 / 83447
• HGNCID: 25319
• Length: 315
• Species: Homo sapiens
• Sequence 2: NP_650891.1
• Gene: DPCoAC / 42429
• FlyBaseID: FBgn0067783
• Length: 365
• Species: Drosophila melanogaster
• Alignment Length: 316
• Identity: 91/316 - (28%)
• Similarity: 145/316 - (45%)
• Gaps: 43/316 - (13%)

Human     5 PAKKKAEKRLFDASSFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDC 69
            |.::|.::.:.       .|::|..|.|::||.:||::|.|:..|:: :....|    ::..:..
  Fly    64 PMRQKIDQVVI-------SLISGAAAGALAKTVIAPLDRTKINFQIR-NDVPFS----FRASLRY 116

Human    70 LVRIPREQGFFSFWRGNLANVIRYFPTQALNFAFKDKYKQLF---MSGVNKEKQFWRWFLANLAS 131
            |......:|..:.||||.|.:.|..|..|:.|...::::::.   ..|.|.:   .|.|||
  Fly   117 LQNTYANEGVLALWRGNSATMARIVPYAAIQFTAHEQWRRILHVDKDGTNTK---GRRFLA---- 174

Human   132 GGAAGATSLCVVYPLDFARTRLGV-DIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQG 195
            |..||.||..:.||||.||.|:.| |...|     ::.|.....||...:|...|::|:..:|.|
  Fly   175 GSLAGITSQSLTYPLDLARARMAVTDRYTG-----YRTLRQVFTKIWVEEGPRTLFRGYWATVLG 234

Human   196 IIVYRASYFGAYDTVK-------GLLPKPKKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRM--M 251
            :|.|..:.|..|:|:|       |    ..|...|||..............|||.|.|||||  |
  Fly   235 VIPYAGTSFFTYETLKREYYEVVG----NNKPNTLVSLAFGAAAGAAGQTASYPLDIVRRRMQTM 295

Human   252 MQSGEAKRQYKGTLDCFVKIYQHEGI-SSFFRGAFSNVLRG-TGGALVLVLYDKIK 305
            ..:.....:|...|:..||||:.||: :.|::|...|.::| ....:....||.||
  Fly   296 RVNTAGGDRYPTILETLVKIYREEGVKNGFYKGLSMNWIKGPIAVGISFSTYDLIK 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC25A31	NP_112581.1	Solcar 1	18..110		23/91 (25%)
		PTZ00169	19..309	CDD:240302	89/302 (29%)
		Solcar 2	123..213		33/97 (34%)
		Solcar 3	220..307		29/90 (32%)
		Important for transport activity. /evidence=ECO:0000250|UniProtKB:P12235	247..252		4/6 (67%)
		Nucleotide carrier signature motif. /evidence=ECO:0000250|UniProtKB:P02722	247..252		4/6 (67%)
DPCoAC	NP_650891.1	PTZ00169	77..336	CDD:240302	83/279 (30%)