Protein Alignment SLC25A31 and Ant2

DIOPT Version :10

• Sequence 1: NP_112581.1
• Gene: SLC25A31 / 83447
• HGNCID: 25319
• Length: 315
• Species: Homo sapiens
• Sequence 2: NP_511110.1
• Gene: Ant2 / 32008
• FlyBaseID: FBgn0025111
• Length: 307
• Species: Drosophila melanogaster
• Alignment Length: 295
• Identity: 204/295 - (69%)
• Similarity: 240/295 - (81%)
• Gaps: 3/295 - (1%)

Human    16 DASSFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFF 80
            |..||..|.:.|||:||::||||||||||||:||||..||||:.:.||||:|||.:|||:||||.
  Fly    14 DLKSFLMDFMMGGVSAAIAKTAVAPIERVKLILQVQEVSKQIAADQRYKGIVDCFIRIPKEQGFS 78

Human    81 SFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLCVVYP 145
            |||||||||||||||||||||||||.||.:|:.||:|.|||||.|..||||||||||||||.|||
  Fly    79 SFWRGNLANVIRYFPTQALNFAFKDVYKSVFLGGVDKHKQFWRHFAGNLASGGAAGATSLCFVYP 143

Human   146 LDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRASYFGAYDTV 210
            ||||||||..|:||| ..|:|.||.||:||:.||||..|||:||.||||||::|||:|||.|||.
  Fly   144 LDFARTRLAADVGKG-GNREFNGLIDCLMKVIKSDGPIGLYRGFIVSVQGIVIYRAAYFGFYDTC 207

Human   211 KGLLPKPKKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGEAKRQ--YKGTLDCFVKIYQ 273
            :..||.||.|||.||:.|||||||.:||.||||||||||||||||..|.:  ||.|..|::.|.:
  Fly   208 RDFLPNPKSTPFYVSWAIAQVVTTVAGIASYPFDTVRRRMMMQSGLKKSEMVYKNTAHCWLVIAK 272

Human   274 HEGISSFFRGAFSNVLRGTGGALVLVLYDKIKEFF 308
            .|||.:||:||.||::|||||||||.|||::|::|
  Fly   273 QEGIGAFFKGALSNIIRGTGGALVLALYDEMKKYF 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC25A31	NP_112581.1	Solcar 1	18..110		69/91 (76%)
		PTZ00169	19..309	CDD:240302	203/292 (70%)
		Solcar 2	123..213		63/89 (71%)
		Solcar 3	220..307		58/88 (66%)
		Important for transport activity. /evidence=ECO:0000250|UniProtKB:P12235	247..252		4/4 (100%)
		Nucleotide carrier signature motif. /evidence=ECO:0000250|UniProtKB:P02722	247..252		4/4 (100%)
Ant2	NP_511110.1	PTZ00169	15..305	CDD:240302	201/290 (69%)