Protein Alignment CASP1 and Decay

DIOPT Version :9

• Sequence 1: NP_001244047.1
• Gene: CASP1 / 834
• HGNCID: 1499
• Length: 404
• Species: Homo sapiens
• Sequence 2: NP_477462.1
• Gene: Decay / 42008
• FlyBaseID: FBgn0028381
• Length: 308
• Species: Drosophila melanogaster
• Alignment Length: 278
• Identity: 72/278 - (25%)
• Similarity: 107/278 - (38%)
• Gaps: 59/278 - (21%)

Human   157 DKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHR 221
            :..:|..:|||:.:::.....:|.|.|.|...|...||..|:.|....:||.|::...|:..| |
  Fly    50 ENCARAGIALILNHKDVKGQKQRVGTERDRDDMEATLQGFGFDVRTFDDLTFSEINDTLKEVA-R 113

Human   222 PEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACR 286
            .:|..:|...|..||||....:..|..|..|      ..::|.....||.:||:|||:..|||||
  Fly   114 EDHSQNDCFVLAVMSHGTEGKVYAKDMSYPV------ERLWNPFLGDNCKTLKNKPKLFFIQACR 172

Human   287 GDSPGVVWFKDSVGVSGNLSLPTTEEFEDDAIKKAHI-----------------EKDFIAFCSST 334
            |                 .:|....||...|:....:                 ..|.:.|.|:.
  Fly   173 G-----------------ANLEKAVEFSSFAVMTRELVPEPAAAVQPITYAIPSTADILVFYSTF 220

Human   335 PDNVSWRHPTMGSVFIGRLIEHM-----QEYACSCDVE------EIFRKVRFSF------EQPDG 382
            ....|:|:...||.||..|...:     .|.|....||      .:.|||.:.:      |..:.
  Fly   221 DKFFSFRNVDDGSWFIQSLCRVLDQAAANEAATPEGVELLRLLTAVNRKVAYEYQSNTKNEALNQ 285

Human   383 RAQMPTTERVTLTRCFYL 400
            ..:||.. ..|||:.|.|
  Fly   286 MKEMPNF-MSTLTKTFQL 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CASP1	NP_001244047.1	CARD_CASP1-like	5..87	CDD:260036
		CASc	153..402	CDD:214521	72/278 (26%)
Decay	NP_477462.1	CASc	54..302	CDD:237997	71/272 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152745
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740