Protein Alignment CASP1 and Damm

DIOPT Version :10

• Sequence 1: XP_016873882.2
• Gene: CASP1 / 834
• HGNCID: 1499
• Length: 448
• Species: Homo sapiens
• Sequence 2: NP_523703.2
• Gene: Damm / 36266
• FlyBaseID: FBgn0033659
• Length: 255
• Species: Drosophila melanogaster
• Alignment Length: 240
• Identity: 68/240 - (28%)
• Similarity: 110/240 - (45%)
• Gaps: 41/240 - (17%)

Human   211 IICNEEF--DSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDS 273
            |:.:|:|  ||...|.|:..|:..:....::|...|:|..|....|:..:::.::  .:..|.|:
  Fly    42 ILNHEQFPQDSQLNRKGSSNDVNALRKTFESLKCRVEVISNPALPDVKNKVKEWS--AKRFTQDA 104

Human   274 TFLVF-MSHGIR-EGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGV 336
            .|::| :|||.| |.|....|.|...|...|..:|     :| |:|..|||::|:|||:|
  Fly   105 GFVLFILSHGDRKEKILACDHREYHLDDDVLFPLF-----RN-PTLSGKPKILIVQACKG----- 158

Human   337 VWFKDSVGVSGNLSLPTTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHM 401
                               ....|| ||.:.| .:|...|.:...:|:|:...|||||..|.|.|
  Fly   159 -------------------PLRADA-KKMNNE-PYIKCYSCSEGYLSYRNENHGSVFIQTLCEAM 202

Human   402 QEYACSCDVEEIFRKVRFSFEQPD---GRAQMPTTERVTLTRCFY 443
            .:|..:.|.:.||:.|:...|:..   |..|:|:.|.....:.||
  Fly   203 DQYGLTRDFQSIFKHVKAEVERRSTMTGSKQVPSEESHNFDKPFY 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CASP1	XP_016873882.2	DD	<77..131	CDD:472698
		CASc	197..446	CDD:214521	68/240 (28%)
Damm	NP_523703.2	Peptidase_C14	42..247	CDD:425803	66/238 (28%)