Protein Alignment CARS1 and eEF1beta

DIOPT Version :9

• Sequence 1: XP_024304469.1
• Gene: CARS1 / 833
• HGNCID: 1493
• Length: 867
• Species: Homo sapiens
• Sequence 2: NP_001286506.1
• Gene: eEF1beta / 45249
• FlyBaseID: FBgn0028737
• Length: 222
• Species: Drosophila melanogaster
• Alignment Length: 221
• Identity: 55/221 - (24%)
• Similarity: 85/221 - (38%)
• Gaps: 84/221 - (38%)

Human    28 LNEHLSTRSYVQGYSLSQADVDAFRQL-SAPPADPQLFHVARWFRHIEALLGSPCGKGQPCRLQA 91
            ||..|:..||:.||:.|:||:..|..| .||.||.  .:||||:|||                 |
  Fly    15 LNAFLADNSYISGYTPSKADLSVFDALGKAPSADN--VNVARWYRHI-----------------A 60

Human    92 SKGRRVQPQWSPPAGTQPCRLHLYNSLTRNKEVFIPQ--DGKKVTWYCCGPTVYDASHMGHARSY 154
            |.....:..||   ||.                 :||  .||        |||..|:
  Fly    61 SFEAAERAAWS---GTP-----------------LPQLAGGK--------PTVAAAA-------- 89

Human   155 ISFDILRRVLKDYFKFDVFYCMNITDIDDKIIKRARQNHL--FEQYREKRP----EAAQLLEDVQ 213
                  :....|....|:|   ...|.:|:..:|.:|..:  :...:.|:|    :::.||:
  Fly    90 ------KPAADDDDDVDLF---GSDDEEDEEAERIKQERVAAYAAKKSKKPALIAKSSVLLD--- 142

Human   214 AALKPFSVKLNETTDPDKKQMLERIQ 239
              :||:.   :||   |.|:|...::
  Fly   143 --VKPWD---DET---DMKEMENNVR 160

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CARS1	XP_024304469.1	GST_C_CysRS_N	3..76	CDD:198343	23/48 (48%)
		PTZ00399	91..858	CDD:240402	32/157 (20%)
eEF1beta	NP_001286506.1	GST_C_eEF1b_like	<3..62	CDD:198341	24/65 (37%)
		EF1_GNE	139..222	CDD:279125	9/33 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2092
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900