Protein Alignment GFI1B and RIM101

DIOPT Version :10

• Sequence 1: NP_001358837.1
• Gene: GFI1B / 8328
• HGNCID: 4238
• Length: 352
• Species: Homo sapiens
• Sequence 2: NP_011836.1
• Gene: RIM101 / 856358
• SGDID: S000001019
• Length: 625
• Species: Saccharomyces cerevisiae
• Alignment Length: 205
• Identity: 49/205 - (23%)
• Similarity: 71/205 - (34%)
• Gaps: 63/205 - (30%)

Human   155 RYSPGMDAYHCVKCNKVFSTPHGLEVHVRRSHSGTRPFACDICGKTFGHAVS-LEQHTHVHSQGI 218
            |.|||..:..|:..:..             ||..|.|:  |:.|.:   ||| ....:...|...
Yeast    74 RMSPGSTSSSCLPYHST-------------SHLNTPPY--DLLGAS---AVSPTTSSSSDSSSSS 120

Human   219 PAGSSPEPA-----PDPPGPHFLRQERSFECRM--CGKAFKRSSTLSTHLLIHSDTRPYPCQFCG 276
            |...:..||     .|..|.   .::.:..|:.  ||..|.:...|..||             |
Yeast   121 PLAQAHNPAGDDDDADNDGD---SEDITLYCKWDNCGMIFNQPELLYNHL-------------C- 168

Human   277 KRFHQKSDMKKHTYIHTGEKPHK-----CQ--VCGKAFSQSSNLITHSRKHTGFKPFSCELCTKG 334
                         :.|.|.|.||     |.  .|.....:..::.:|.|.|...|||.|..|:|.
Yeast   169 -------------HDHVGRKSHKNLQLNCHWGDCTTKTEKRDHITSHLRVHVPLKPFGCSTCSKK 220

Human   335 FQRKVDLRRH 344
            |:|..||::|
Yeast   221 FKRPQDLKKH 230

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GFI1B	NP_001358837.1	C2H2 Zn finger	165..186	CDD:275368	1/20 (5%)
		C2H2 Zn finger	194..214	CDD:275368	5/20 (25%)
		C2H2 Zn finger	244..264	CDD:275368	7/21 (33%)
		COG5048	252..>329	CDD:227381	17/83 (20%)
		C2H2 Zn finger	272..292	CDD:275368	1/19 (5%)
		zf-H2C2_2	284..309	CDD:463886	7/31 (23%)
		C2H2 Zn finger	300..320	CDD:275368	4/21 (19%)
		C2H2 Zn finger	328..345	CDD:275368	8/17 (47%)
RIM101	NP_011836.1	COG5048	41..571	CDD:227381	49/205 (24%)
		C2H2 Zn finger	151..171	CDD:275368	7/46 (15%)
		C2H2 Zn finger	184..206	CDD:275368	4/21 (19%)
		C2H2 Zn finger	214..234	CDD:275368	8/17 (47%)