DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ATL43 and RNF38

DIOPT Version :9

Sequence 1:	NP_196200.3	Gene:	ATL43 / 830466	AraportID:	AT5G05810	Length:	407	Species:	Arabidopsis thaliana
Sequence 2:	NP_073618.3	Gene:	RNF38 / 152006	HGNCID:	18052	Length:	515	Species:	Homo sapiens

Alignment Length:	166	Identity:	53/166 - (31%)
Similarity:	76/166 - (45%)	Gaps:	34/166 - (20%)

- Green bases have known domain annotations that are detailed below.

plant    36 PPPLP-------------PPSPPPRHNFTSSLMPGIAVVIAVLTAFFSLTFLLLLYVKHCKRRNG 87
            ||.:|             |..|||.|   .||:|.:..::.|..| ...||...|.|:..:..|.
Human   360 PPFMPRRLTGRSRYRSQQPIPPPPYH---PSLLPYVLSMLPVPPA-VGPTFSFELDVEDGEVENY 420

plant    88 SVYVNHPQRFAITRYGGGYYNGGGVVGGRKNSGIDRSVIESLPVFRFGALSGHKDGLECAVCLAR 152
            ...:|..:|                :|..|..|:.::.||.||.:||...:...:...|.||:..
Human   421 EALLNLAER----------------LGEAKPRGLTKADIEQLPSYRFNPNNHQSEQTLCVVCMCD 469

plant   153 FEPTEVLRLLPKCKHAFHVECVDTWLDAHSTCPLCR 188
            ||..::||:|| |.|.||.:|||.||.|:.|||:||
Human   470 FESRQLLRVLP-CNHEFHAKCVDKWLKANRTCPICR 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ATL43	NP_196200.3	RING-H2_EL5_like	145..188	CDD:319375	22/42 (52%)
RNF38	NP_073618.3	Bipartite nuclear localization signal 1	57..71
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	73..141
		Bipartite nuclear localization signal 2	115..131
		RING-H2_RNF38_like	460..504	CDD:319386	22/44 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X146
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910