Protein Alignment CAPZA2 and cpa

DIOPT Version :10

• Sequence 1: NP_006127.1
• Gene: CAPZA2 / 830
• HGNCID: 1490
• Length: 286
• Species: Homo sapiens
• Sequence 2: NP_611539.1
• Gene: cpa / 37387
• FlyBaseID: FBgn0034577
• Length: 286
• Species: Drosophila melanogaster
• Alignment Length: 279
• Identity: 172/279 - (61%)
• Similarity: 216/279 - (77%)
• Gaps: 2/279 - (0%)

Human     8 LSDEEKVRIAAKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNLDQFTPVKIEGYED 72
            ::|.|||||.:.||:|||||||||||||||.||.||.||::||:|||||||.||.|||:|||.:.
  Fly     6 ITDAEKVRIVSDFILHAPPGEFNEVFNDVRELLKNDTLLKDGASHAFAQYNKDQLTPVRIEGTDH 70

Human    73 QVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPCEVENAVESWRTSVETALRAYVKEHYP 137
            ..:|:||.|||||:|.||:.:..||:|||||||:|.:..|.:...|.||.:::....||...||.
  Fly    71 NAIISEHNDLGNGRFYDPRTKQAFKYDHLRKEASDYQDVEADATAEPWRAALDLETLAYTASHYR 135

Human   138 NGVCTVYGKKIDGQQTIIACIESHQFQAKNFWNGRWRSEWKFTIT--PSTTQVVGILKIQVHYYE 200
            :||.:|:||....|.|:..|||.||||.||:|||||||:|..|..  ..|.::.|:||:||||||
  Fly   136 HGVSSVFGKAQGNQITLTICIEDHQFQPKNYWNGRWRSQWHVTFQAGSGTAELKGVLKVQVHYYE 200

Human   201 DGNVQLVSHKDIQDSLTVSNEVQTAKEFIKIVEAAENEYQTAISENYQTMSDTTFKALRRQLPVT 265
            ||||||||.|:.::|:.||||.|.|||.|:::|.||||||.||||||||||||||||:|||||:|
  Fly   201 DGNVQLVSSKECRESVVVSNEQQVAKEVIRLIEDAENEYQLAISENYQTMSDTTFKAMRRQLPIT 265

Human   266 RTKIDWNKILSYKIGKEMQ 284
            ||||||:||:||.||||::
  Fly   266 RTKIDWSKIVSYSIGKELK 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAPZA2	NP_006127.1	F-actin_cap_A	17..282	CDD:460142	164/266 (62%)
cpa	NP_611539.1	F-actin_cap_A	15..282	CDD:460142	164/266 (62%)