Protein Alignment CAPZA1 and cpa

DIOPT Version :10

• Sequence 1: XP_016857913.1
• Gene: CAPZA1 / 829
• HGNCID: 1488
• Length: 318
• Species: Homo sapiens
• Sequence 2: NP_611539.1
• Gene: cpa / 37387
• FlyBaseID: FBgn0034577
• Length: 286
• Species: Drosophila melanogaster
• Alignment Length: 311
• Identity: 180/311 - (57%)
• Similarity: 216/311 - (69%)
• Gaps: 34/311 - (10%)

Human     8 VSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYED 72
            ::|.|||||.:.||.|||||||||||||||.||.||.||::||:|||||||.||.|||:|||.:.
  Fly     6 ITDAEKVRIVSDFILHAPPGEFNEVFNDVRELLKNDTLLKDGASHAFAQYNKDQLTPVRIEGTDH 70

Human    73 QVLITEHGDLGNSRFLDPRNKISFKFDHLRKEASDPQPEEADGGLKSWRESCDSALRAYVKDHYS 137
            ..:|:||.||||.||.|||.|.:||:|||||||||.|..|||...:.||.:.|....||...||.
  Fly    71 NAIISEHNDLGNGRFYDPRTKQAFKYDHLRKEASDYQDVEADATAEPWRAALDLETLAYTASHYR 135

Human   138 NGFCTVYAKTIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTIT--PPTAQVVGVLKIQVHYYE 200
            :|..:|:.|....|.|:..|||.|||||||:|||||||:|..|..  ..||::.||||:||||||
  Fly   136 HGVSSVFGKAQGNQITLTICIEDHQFQPKNYWNGRWRSQWHVTFQAGSGTAELKGVLKVQVHYYE 200

Human   201 DGNVQLVSHKDVQDSLTVSNEAQTAKEFIKIIENAENEYQGTQAYPLTIALLFCSQPAPFLFKQL 265
            ||||||||.|:.::|:.||||.|.|||.|::||:|||||
  Fly   201 DGNVQLVSSKECRESVVVSNEQQVAKEVIRLIEDAENEY-------------------------- 239

Human   266 IFNYLLQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGKEMQ 316
                  |.||||||||||||||||:|||||:|||||||:||:||.||||::
  Fly   240 ------QLAISENYQTMSDTTFKAMRRQLPITRTKIDWSKIVSYSIGKELK 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAPZA1	XP_016857913.1	F-actin_cap_A	17..314	CDD:460142	172/298 (58%)
cpa	NP_611539.1	F-actin_cap_A	15..282	CDD:460142	172/298 (58%)