DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment AT4G28370 and dsc1

DIOPT Version :9

Sequence 1:	NP_001328219.1	Gene:	AT4G28370 / 828953	AraportID:	AT4G28370	Length:	562	Species:	Arabidopsis thaliana
Sequence 2:	NP_595266.2	Gene:	dsc1 / 2541251	PomBaseID:	SPBC947.10	Length:	695	Species:	Schizosaccharomyces pombe

Alignment Length:	649	Identity:	145/649 - (22%)
Similarity:	240/649 - (36%)	Gaps:	201/649 - (30%)

- Green bases have known domain annotations that are detailed below.

plant    49 FGRKQEAEVGPFSAWNITGTYRGTWKFLNS--LNSSSKFQD--FQKENGNSVVELVAVPTKITGV 109
            ||:     |.|...|:.|         |.:  ::.|.:|..  ::..:|||           .|:
pombe   109 FGK-----VSPNVTWHTT---------LRNIVMSQSGRFSANLYEYVDGNS-----------DGI 148

plant   110 HYV------QGVVVFHDVFDNEQ---------------NVGGAQI--------------NLEGVY 139
            .:|      ....|:|..|..::               |.||..:              .|:|..
pombe   149 SFVLNLENNNDTSVYHMTFHGDRVKPINVFLGSTDVTPNFGGVDVIPWLLKDSPYKDAPPLDGTE 213

plant   140 IWPFRQLRLVANSGKESDSGQEDNNLLSNPYHLLGIFSSQVFQESPRDRLLKRKLSPVNEMEKHC 204
            .:|..|.|    |.:..::..:|...:.        :|..||:|.
pombe   214 YFPLLQNR----SLERIETRLQDAQTVG--------WSPLVFEEE-------------------- 246

plant   205 NIEIAAQVSRVASSENNG---------DKNYYHMEGL--MESPGVGDDGDCFSP------LLLNA 252
              |:.........::|.|         :..:||.:|:  .:.|.|...|..:||      ...|.
pombe   247 --EVTCSAFVFLHNKNTGLDKETLKAIENEFYHPQGVSTQKMPEVFVSGLVYSPDCNVAFTFSNT 309

plant   253 TSVNVEVYYNKAVNYTLMVTFVSFLQVLLLIRQMEHGNTQSGAAKVSIVMIGQQAIMDAYLCLLH 317
            ......|..|..|.::.:..|:...|:.:|:|||.. |:.|...::|.:.|..||.:|||:.:..
pombe   310 KGPRNFVLENHLVRFSSLYIFIVLSQIFVLLRQMRI-NSPSHVQRLSFLTIAMQAGLDAYIAIFF 373

plant   318 LTAGILVESLFNAFATAAFFKFVVFSIFEMRYLLAIWKA-------------------------- 356
            |:...::|..:..|.:.||...|...:|.||||..|.:.
pombe   374 LSTNAVIEKGYLPFVSVAFLSLVPSVMFTMRYLALILRVQNSNMPPPAPRPVTNNSSNNNTNQSN 438

plant   357 -------TRPSNSGEGWETM------------------RRELSFLYSRFYGILLGGIL------- 389
                   ..||.:.:..||.                  :|:.|.:..|||.|:|...:
pombe   439 ASNENSPNAPSAANDNTETTTVNPPQEDDQPMTQHERDQRDWSAVCLRFYFIILVVCIASLYSAF 503

plant   390 --IMYQFHNYMQPILLLMYSFWIPQIVANVVRDSRKPLHPYYILGMTATRLAIPLYVFGCPHNFM 452
              ::|:|: ::..::...||||||||:.||.:.:.:.....||||.:..||.:||.:|......:
pombe   504 WPVIYRFY-FISALIFTSYSFWIPQIIQNVKQGTSRSFTWTYILGASVLRLYLPLAIFIDSELIL 567

plant   453 RVEPNKVWCICLCTFMGLQAVILLLQHYFGSRCFVPRQMLPEK--YNYH--------RRFNRDVS 507
            ...|...:.:.|..:|..|.::||:|...|.|.|:|::.....  |:||        ..|.||.:
pombe   568 GFPPKYFFALGLVLWMLFQVLVLLVQDTLGPRFFLPKKFFLSSPVYDYHPVIQQDDLEAFMRDAN 632

plant   508 RTTDCVICMTAIDLRQHTS-----------DCMVTPCEHFFHSGCLQRWMDIKMECPTCRRSLP 560
               .|.|||..|:|....|           :.|:|||.|.:|..||.:||:.:..||.||..||
pombe   633 ---VCPICMQPIELVSTGSTLNPASMMVRRNYMLTPCHHLYHRQCLLQWMETRSICPVCRCHLP 693

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AT4G28370	NP_001328219.1	DUF2921	<408..486	CDD:371393	26/77 (34%)
AT4G28370	NP_001328219.1	zf-RING_2	510..556	CDD:372655	19/56 (34%)
dsc1	NP_595266.2	zf-RING_2	632..689	CDD:290367	19/59 (32%)
dsc1	NP_595266.2	zf-rbx1	<633..689	CDD:289448	19/55 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	100	1.000	Domainoid score	I1911
eggNOG	1	0.900	-	-		E1_COG5540
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H97221
Inparanoid	1	1.050	136	1.000	Inparanoid score	I1463
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0014593
OrthoInspector	1	1.000	-	-		otm8763
orthoMCL	1	0.900	-	-		OOG6_105468
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11848
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.760