DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment RIN2 and amfr

DIOPT Version :9

Sequence 1:	NP_001328533.1	Gene:	RIN2 / 828626	AraportID:	AT4G25230	Length:	578	Species:	Arabidopsis thaliana
Sequence 2:	NP_001017083.1	Gene:	amfr / 549837	XenbaseID:	XB-GENE-923086	Length:	635	Species:	Xenopus tropicalis

Alignment Length:	608	Identity:	156/608 - (25%)
Similarity:	240/608 - (39%)	Gaps:	184/608 - (30%)

- Green bases have known domain annotations that are detailed below.

plant    20 LQVWTELS-----LDRLRA----DGLIAKNISLGDSEHALEL-------------LLGSYFTIAL 62
            |:.:|.||     |..|.|    .|..|:...|...|...:|             |:.....:.:
Frog    14 LRTYTGLSGLLLGLSLLSAYRSLSGEAAERSMLEGEEAGAQLPPEPVDLVELFRYLVSDSLGVWV 78

plant    63 LTNFVLNVYILLVLSLKTLFFGDLYDVETKKLVERLANYIIYKGTFLPLVI-PPTIFQGVLWTVW 126
            |.|.|..:.:|:...::.:.||.|...|.:.|.::..|:|.||..|:..|: ..|:.:.|||.:|
Frog    79 LVNTVCCLLMLIAKLIQHVVFGPLRVGERQHLKDKFWNFIFYKFIFIFGVLNVQTVEEVVLWFLW 143

plant   127 LTVLCTLKMFQALARDRLERLNASPSSTPWTYFRVYSVLFLVLSVDMFWIKLSLMTYNTIGSAVY 191
            ...|..|.:...|.:||.|.|:.||::....:.||     |||        |::|.....|.||.
Frog   144 FAGLLFLHLMVQLCKDRFEYLSFSPTTPMSCHMRV-----LVL--------LNIMLLACCGLAVL 195

plant   192 LLLLFEPCSIAFETLQALLIHGFQLLDMWINHLAVKNSDCQRSKFIDSMTAGSLL---------- 246
                   |:||..|      ||       ::.||...::|.   .:.:.|...:|
Frog   196 -------CAIAGYT------HG-------MHTLAFMAAECM---LVTTRTTHVVLRYVIHLWDLN 237

plant   247 -----EWKGLLNRNLGFFLDMATLVMALGHYLHIWWLHGIAFHLVDAVLFLNIRALLSAILKRI- 305
                 |.||.......|.::::.|.:.|.|::|:.....|...:...|:|:.:|.|.....:||
Frog   238 HEGTWEGKGTYVYYTDFVMELSHLSIDLMHHIHMLLFGNIWLSMASLVIFMQLRHLFHEFQRRIR 302

plant   306 --KGYIKLRIALGALHAALPDATSEELRAYDDECAICREPMAKAKRLHCNHLFHLGCLRSWLDQG 368
              |.|:::   :|.:.|....||.|||.|..|:||||.:.|..|::|.|.||||..||||||:|.
Frog   303 RHKNYLRV---VGNMEAHFAVATPEELEANSDDCAICWDSMQSARKLPCGHLFHNSCLRSWLEQD 364

plant   369 LNEVYSCPTCRKPLFVG---RT------ENEVNPRTVEVSSDEQLARQLERQNNPVHALATGLFP 424
            .    ||||||..|.:.   ||      ||: :...|.::..|...| |...|:..|.
Frog   365 T----SCPTCRMSLNMADGTRTRVEQQRENQ-DQNAVPLAVTEGRPR-LNHHNHFFHF------- 416

plant   425 AEVPDSVENDTSRNLGLDPSWLQTWSSQGSDVAGPSTTSRTVGLGRVQMMMRHLASVGESYAQTA 489
                     |.||    ..|||.::|                    |::|  |..::
Frog   417 ---------DGSR----FASWLPSFS--------------------VEVM--HTTNI-------- 438

plant   490 LDDAAWSLWPMNPSQASTSSTTVPPGNGGRTGGLHLRTVSNTTNESLTNILAMAETVREVMPHVP 554
                      :..:|||.|                             .:.|||..|.::.|.||
Frog   439 ----------LGLAQASNS-----------------------------QLNAMARQVLDMFPQVP 464

plant   555 DEIIFQDLQRTNSVAVTVNNLLQ 577
            ..::.||||.|.||.:|.:|:|:
Frog   465 YHLVLQDLQLTRSVEITTDNILE 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RIN2	NP_001328533.1	None
amfr	NP_001017083.1	HRD1	75..>374	CDD:227568	101/341 (30%)
		RING-H2_AMFR	331..374	CDD:319369	26/46 (57%)
		RING-H2 finger (C3H2C3-type)	333..370	CDD:319369	22/40 (55%)
		CUE_AMFR	450..490	CDD:270604	17/38 (45%)
		G2BR	564..589	CDD:375868
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	168	1.000	Inparanoid score	I1858
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D897451at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3836
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.060