DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment VSR7 and matn4

DIOPT Version :9

Sequence 1:	NP_001190777.1	Gene:	VSR7 / 827757	AraportID:	AT4G20110	Length:	628	Species:	Arabidopsis thaliana
Sequence 2:	XP_005155921.1	Gene:	matn4 / 497348	ZFINID:	ZDB-GENE-050208-64	Length:	944	Species:	Danio rerio

Alignment Length:	620	Identity:	116/620 - (18%)
Similarity:	175/620 - (28%)	Gaps:	268/620 - (43%)

- Green bases have known domain annotations that are detailed below.

plant   187 KRVEYELWTNSNDEC-----------GARCDEQMDFVKNFKGHAQILEKGGYTAFTPHYITWFCP 240
            |.::|  .:..||.|           ..||||.....::.|....|               .:|.
Zfish   294 KMIDY--CSFGNDSCEHKCVSVLNGFNCRCDEGYSLNEDLKTCTMI---------------DYCS 341

plant   241 FQFINSPHCKSQCIN--HGRYCAPDPEDNFREGYEGKDVVLENLRQLCVHRVANESSRPWVWWDY 303
            |   .:..|:.:|::  ...||      ..|:||                 ..||........||
Zfish   342 F---GNDSCEHECVSVLQSFYC------QCRDGY-----------------TLNEDETTCTMIDY 380

plant   304 ---------------VTDFHSRCSMKEKKYSIDCAESYESLRLFSDLPIEKIKKCIGDPEADTEN 353
                           :..||.||:   :.||::                :.:|.|.........|
Zfish   381 CSFGNDSCEHECVSVLNGFHCRCN---EGYSLN----------------DDLKTCTMIDYCSFGN 426

plant   354 QVLRTEQVSQIG----RGNRGDVTILPTLVINNAQYRGRLERTAVLKAICAGFNETSE------- 407
            .....|.||.:.    |.|.|       ..:|:.      ::|..:...|:..|::.|
Zfish   427 DSCEHECVSVLKGFHCRCNDG-------YTLNDD------KKTCTMIDYCSFGNDSCEHECVSVL 478

plant   408 ---PAICLNTGLETNE------------------------------CLENNGGCWQDTKANIT-- 437
               ..|| |.|...|:                              |:.|:|....|.|...|
Zfish   479 KGFHCIC-NEGYSLNDDKKTCTMIDYCSFGNDSCEHECVSVLKGFHCICNDGYSLNDDKKTCTMI 542

plant   438 ------------ACQDTFRGRLCECPVVKGVQYKGDGYTSCT--PYGPARCTMNNGGCWSD---- 484
                        .|....:|..|.|.  :|....|| ..:||  .|    |:..|..|..:
Zfish   543 DYCSFGNDSCEHQCVSVLKGFNCRCN--EGYSLNGD-LKTCTMIDY----CSFGNDSCEHECVSV 600

plant   485 -------TRNGLTFSA----------CS----------DSVSTG--CKCPEGF--QGDGLTCEDI 518
                   .::|.|.:.          ||          .||..|  |:|.||:  |.||.||:..
Zfish   601 LNGFHCRCKDGYTLNEDKKTCTMIDYCSFGNHSCDHHCVSVLNGFFCRCNEGYTLQEDGKTCQSD 665

plant   519 NECKERSVCQCSGC--RCKNSWGGYKCSCSGDRLYINDQDTC-------------IERYGSKTAW 568
            |.|....    .||  :|.::.|.|.|.|....:..:|..:|             |:  |||:..
Zfish   666 NLCNTVE----HGCEYQCVSTPGSYHCICPEGHVLQDDGKSCGTCRTSNIDLVLLID--GSKSVR 724

plant   569 WLTFLI-----------LAIVAVAGLAGYIFYKYRFRS---------------------YMDSEI 601
            ...|.:           |.:.|.....|.:.|..|.|:                     ||:...
Zfish   725 PQNFELVKQFVNQVVDQLDVSAKGTRVGLVQYSSRVRTEFPLSMYHSKDEIKKAVMNVEYMEKGT 789

plant   602 MT-------IMSQYMPLESQRARE--VPSEAEPFT 627
            ||       :.:.:...|..|..|  :|.....||
Zfish   790 MTGLALKHMVENSFSEAEGARPAEKNIPRVGLVFT 824

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
VSR7	NP_001190777.1	PA_VSR	53..176	CDD:239040
		VESA1_N	<494..>564	CDD:289551	26/98 (27%)
		EGF_CA	517..>545	CDD:238011	8/29 (28%)
matn4	XP_005155921.1	vWFA	32..251	CDD:294047
		FXa_inhibition	258..293	CDD:291342
		FXa_inhibition	299..334	CDD:291342	8/34 (24%)
		FXa_inhibition	340..375	CDD:291342	11/60 (18%)
		FXa_inhibition	381..416	CDD:291342	7/53 (13%)
		FXa_inhibition	422..457	CDD:291342	8/47 (17%)
		vWFA	<454..497	CDD:294047	9/43 (21%)
		FXa_inhibition	504..539	CDD:291342	5/34 (15%)
		vWFA	<536..579	CDD:294047	9/45 (20%)
		FXa_inhibition	586..621	CDD:291342	5/34 (15%)
		vWFA	<618..661	CDD:294047	12/42 (29%)
		vWFA	<659..702	CDD:294047	13/46 (28%)
		vWFA	711..944	CDD:294047	21/116 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1618
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000