DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment VSR7 and ltbp4

DIOPT Version :9

Sequence 1:	NP_001190777.1	Gene:	VSR7 / 827757	AraportID:	AT4G20110	Length:	628	Species:	Arabidopsis thaliana
Sequence 2:	XP_031747134.1	Gene:	ltbp4 / 100488208	XenbaseID:	XB-GENE-992148	Length:	1805	Species:	Xenopus tropicalis

Alignment Length:	447	Identity:	94/447 - (21%)
Similarity:	135/447 - (30%)	Gaps:	187/447 - (41%)

- Green bases have known domain annotations that are detailed below.

plant   199 DEC---------GARCDEQMDFVKNFKGHAQILEKGGYTAFTPHYITWFCPFQFINSPH---CK- 250
            |||         ..||:.                       ||......||..:..:|.   |:
Frog   833 DECRISPRRFCLSGRCEN-----------------------TPGSFLCVCPVGYTANPQGTDCQD 874

plant   251 -SQCINHGRYC----APDPEDNFR----EGY----EGKDVVLENLRQLCVHRVANESSRPWVWWD 302
             .:|....|.|    ..:...:||    .||    :|.:         |:.  .||...|
Frog   875 TDECRQTPRICGSGRCQNTPGSFRCSCPVGYRLTPQGNE---------CID--INECENP----- 923

plant   303 YVTDFHSRCSMKE---KKYSIDCAESYESLRLFSDLPIEKIKKCIGDPEADTENQVLRTEQVSQI 364
                  ..|:.:|   ...|..|.:.:...||.:...:: |.:|..|.......:.:.||
Frog   924 ------GACAGQECLNTPGSFQCRQCHSGYRLQNRRCVD-INECQTDSACGRHGKCINTE----- 976

plant   365 GRGNRGDVTILPTLVINNAQYRGRLERTAVLKAICAGFNETSEPAICLNTGLETNECLENNGGCW 429
               ...:...||...:|:   |.|          |...||..|...|...|
Frog   977 ---GSFECECLPGYHLND---RNR----------CTDINECLEGDFCFPRG-------------- 1011

plant   430 QDTKANITACQDTFRGRLCECPVVKGVQYKGDGYTSCTPYGPARC---------TMNNGG----- 480
                    .||:|....:|.|         .:||.: ||.| |.|         |:..||
Frog  1012 --------ECQNTEGSYICVC---------AEGYVT-TPDG-ASCVDKDECQQGTLCQGGRCINT 1057

plant   481 -----CWSDTRNGLTF--SACSD----------------------SVSTGCKCPEGFQ----GDG 512
                 |...|...:||  :||:|                      |.....:|..|::    ||
Frog  1058 QGSFQCQCPTGFRVTFNKAACTDIDECQERGTSLCGTQSCENTLGSYRCIAQCDTGYRLTASGD- 1121

plant   513 LTCEDINECKERSVCQCSGCRCKNSWGGYKCSC------SGDRLYINDQDTCIERYG 563
              |||||||...::|. ....|||..|.|:|:|      |.:..:..|.|.|:| ||
Frog  1122 --CEDINECANSTICG-DNAVCKNLLGSYRCTCNWGHEMSSEGQHCIDVDECLE-YG 1174

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
VSR7	NP_001190777.1	PA_VSR	53..176	CDD:239040
		VESA1_N	<494..>564	CDD:289551	29/102 (28%)
		EGF_CA	517..>545	CDD:238011	12/27 (44%)
ltbp4	XP_031747134.1	EGF_CA	492..>522	CDD:214542
		TB	553..595	CDD:395554
		cEGF	727..750	CDD:403760
		EGF_CA	747..787	CDD:311536
		EGF_CA	789..830	CDD:214542
		EGF_CA	831..872	CDD:311536	10/61 (16%)
		EGF_CA	874..914	CDD:311536	8/48 (17%)
		EGF_CA	916..955	CDD:214542	9/51 (18%)
		EGF_CA	956..996	CDD:214542	10/61 (16%)
		EGF_CA	997..1038	CDD:214542	16/73 (22%)
		EGF_CA	1039..1070	CDD:214542	5/30 (17%)
		EGF_CA	1124..1165	CDD:238011	14/41 (34%)
		EGF_CA	1210..1245	CDD:238011
		TB	1333..1374	CDD:395554
		EGF_CA	1431..>1459	CDD:214542
		TB	1495..1536	CDD:395554
		PHA03247	<1543..1695	CDD:223021
		EGF_CA	1757..1796	CDD:214542
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910