DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AT4G09560 and RNF167

DIOPT Version :9

Sequence 1:	NP_192694.2	Gene:	AT4G09560 / 826540	AraportID:	AT4G09560	Length:	448	Species:	Arabidopsis thaliana
Sequence 2:	NP_001357232.1	Gene:	RNF167 / 26001	HGNCID:	24544	Length:	374	Species:	Homo sapiens

Alignment Length:	371	Identity:	103/371 - (27%)
Similarity:	162/371 - (43%)	Gaps:	79/371 - (21%)

- Green bases have known domain annotations that are detailed below.

plant    27 NSTSLSFDDVEATFTPMIKRSDQGGVLYVAEPLDACSDLVNTVNVKNGTTVSPP----------Y 81
            ::.|:.|.|:.|.|...:.:....|.|..|.|.:|||            .::||          .
Human    32 HNASMDFADLPALFGATLSQEGLQGFLVEAHPDNACS------------PIAPPPPAPVNGSVFI 84

plant    82 VLIIRGGCSFEDKIRNAQKAGYKAAIVYDYEDFGFLVSMAGN----PSGVLIYGTFVSKATGEVL 142
            .|:.|..|:|:.|:.|||||||.||:|::... ..|::|..|    ...:.|...|:.:.:.|.|
Human    85 ALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNS-NELLNMVWNSEEIQQQIWIPSVFIGERSSEYL 148

plant   143 KE-YAGRTDFEVWLMP--SFETSAWSIMAISFISL--LAMSAV-LATCF----FVRRHRVRRRRI 197
            :. :.......|.|:|  :|....:.|.....:.|  |||.|| :|.|.    .::|:|:.:.::
Human   149 RALFVYEKGARVLLVPDNTFPLGYYLIPFTGIVGLLVLAMGAVMIARCIQHRKRLQRNRLTKEQL 213

plant   198 LALNGNDFHRMPKSMI----IRMPTTIFNGICDEATTSILCCICLENYEKGDKLRILPCHHKFHV 258
            ..:..:|:.:...|.:    :.:||.:.:..........:|.|||:.||.|||||:|||.|.:|.
Human   214 KQIPTHDYQKALNSSMFCPDLILPTCLISSTGFVGDQYDVCAICLDEYEDGDKLRVLPCAHAYHS 278

plant   259 ACVDLWLGQRKSFCPVCKRDA--------------------RSISTDKPPSEHTPFLSRTPSMTP 303
            .|||.||.|.:..||:||:..                    .....|.|.||.||.|..:|:: |
Human   279 RCVDPWLTQTRKTCPICKQPVHRGPGDEDQEEETQGQEEGDEGEPRDHPASERTPLLGSSPTL-P 342

plant   304 TSSFLLSSSSTTPLQSSHELPISIRVDPSLPSTS--MQPHTVPMYL 347
            ||   ..|.:..||           |.|. |||.  :.|.:.|:.|
Human   343 TS---FGSLAPAPL-----------VFPG-PSTDPPLSPPSSPVIL 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AT4G09560	NP_192694.2	PA_C_RZF_like	19..163	CDD:239038	40/152 (26%)
AT4G09560	NP_192694.2	zf-RING_2	234..276	CDD:290367	24/41 (59%)
RNF167	NP_001357232.1	PA_C_RZF_like	20..170	CDD:239038	40/150 (27%)
		RING-H2_RNF167	252..297	CDD:319711	25/44 (57%)
		RING-H2 finger (C3H2C3-type)	254..295	CDD:319711	24/40 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	71	1.000	Domainoid score	I4059
eggNOG	1	0.900	-	-		E1_KOG4628
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	136	1.000	Inparanoid score	I2220
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	1	1.000	-	-		FOG0001489
OrthoInspector	1	1.000	-	-		mtm1436
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X670
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.830