Protein Alignment CAPNS1 and CalpC

DIOPT Version :10

• Sequence 1: XP_005259352.1
• Gene: CAPNS1 / 826
• HGNCID: 1481
• Length: 322
• Species: Homo sapiens
• Sequence 2: NP_573118.2
• Gene: CalpC / 32597
• FlyBaseID: FBgn0260450
• Length: 681
• Species: Drosophila melanogaster
• Alignment Length: 207
• Identity: 56/207 - (27%)
• Similarity: 98/207 - (47%)
• Gaps: 11/207 - (5%)

Human    59 MRILGGVISAISEAAAQ----YNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATE 119
            :||||.....:|....|    .:|.|....|........:.:.|.|:..::.|||.::..::..|
  Fly   470 VRILGTGSFRLSCLETQTMILLDPFPALKSTDAERCGGPKVKSVCQYEPVYMQLADENKTINCFE 534

Human   120 LMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTD 184
            |..:|...:..  |.......||.||.::|:.|...:|::.|::||....|:|.||.::|.:..:
  Fly   535 LHELLEACLPN--DYIKGCANIDICRQVIALQDRSGSGRITFQQFKTFMVNLKSWQGVFKMYTKE 597

Human   185 RSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKD 249
            ::|.:.:..|..|....||.|:..:.|.:|:||..:.|.:...:|:|.::.|...|..| .|...
  Fly   598 KAGILRAERLRDALCDIGFQLSTDIMNCLIQRYIRKDGTLRLSDFVSAVIHLTTAFNQF-HLKNY 661

Human   250 GTGQIQVNIQEV 261
            |    |||:.||
  Fly   662 G----QVNVIEV 669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAPNS1	XP_005259352.1	EFh_PEF_CPNS1_2	100..260	CDD:320063	44/159 (28%)
		EF-hand motif	100..128	CDD:320063	7/27 (26%)
		EF-hand motif	142..172	CDD:320063	10/29 (34%)
		EF-hand motif	173..203	CDD:320063	6/29 (21%)
		EF-hand motif	209..237	CDD:320063	7/27 (26%)
CalpC	NP_573118.2	CysPc	7..329	CDD:238004
		Calpain_III	346..483	CDD:238132	5/12 (42%)
		EFh_PEF	515..680	CDD:355382	46/162 (28%)
		EF-hand motif	515..543	CDD:320054	7/27 (26%)
		EF-hand motif	556..585	CDD:320054	9/28 (32%)
		EF-hand motif	586..615	CDD:320054	6/28 (21%)
		EF-hand motif	622..650	CDD:320054	7/27 (26%)
		EF-hand motif	652..680	CDD:320054	9/23 (39%)