Protein Alignment CAPNS1 and Capns1

DIOPT Version :9

• Sequence 1: XP_005259352.1
• Gene: CAPNS1 / 826
• HGNCID: 1481
• Length: 322
• Species: Homo sapiens
• Sequence 2: NP_033925.2
• Gene: Capns1 / 12336
• MGIID: 88266
• Length: 268
• Species: Mus musculus
• Alignment Length: 261
• Identity: 247/261 - (94%)
• Similarity: 254/261 - (97%)
• Gaps: 2/261 - (0%)

Human     1 MFLVNSFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGG-GGGGGGGGTAMRILGG 64
            ||||||||| ||||||||||||||||||||||||||.|||||||||.| ||||||||||||||||
Mouse     1 MFLVNSFLK-GGGGGGGGGGLGGGLGNVLGGLISGAAGGGGGGGGGMGLGGGGGGGGTAMRILGG 64

Human    65 VISAISEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVT 129
            ||||||||||||||||||||:|||||||||||||||||:||.|||||||||||||||||||||||
Mouse    65 VISAISEAAAQYNPEPPPPRSHYSNIEANESEEVRQFRKLFVQLAGDDMEVSATELMNILNKVVT 129

Human   130 RHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSEL 194
            |||||||||||||||||||||||||||||||||||||||||||:||||||:|||||||||.|.||
Mouse   130 RHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKKWQAIYKRFDTDRSGTIGSHEL 194

Human   195 PGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQ 259
            ||||||||||||||||:||||||:||||||||||||||||||||||||||||||:||||||||||
Mouse   195 PGAFEAAGFHLNEHLYSMIIRRYADESGNMDFDNFISCLVRLDAMFRAFKSLDKNGTGQIQVNIQ 259

Human   260 E 260
            |
Mouse   260 E 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAPNS1	XP_005259352.1	EFh_PEF_CPNS1_2	100..260	CDD:320063	150/159 (94%)
		EF-hand motif	100..128	CDD:320063	25/27 (93%)
		EF-hand motif	142..172	CDD:320063	29/29 (100%)
		EF-hand motif	173..203	CDD:320063	25/29 (86%)
		EF-hand motif	209..237	CDD:320063	25/27 (93%)
Capns1	NP_033925.2	EFh_PEF_CPNS1_2	100..268	CDD:320063	152/161 (94%)
		EF-hand motif	100..128	CDD:320063	25/27 (93%)
		EF-hand motif	142..172	CDD:320063	29/29 (100%)
		EF-hand motif	173..203	CDD:320063	25/29 (86%)
		EF-hand motif	209..237	CDD:320063	25/27 (93%)
		EF-hand motif	238..268	CDD:320063	22/23 (96%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83969826
Domainoid	1	1.000	210	1.000	Domainoid score	I24127
eggNOG	1	0.900	-	-		E1_KOG0037
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1327
Inparanoid	1	1.050	516	1.000	Inparanoid score	I11936
Isobase	1	0.950	-	0	Normalized mean entropy	S3436
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG46114
OrthoDB	1	1.010	-	-		D1330600at2759
OrthoFinder	1	1.000	-	-		FOG0004825
OrthoInspector	1	1.000	-	-		oto116515
orthoMCL	1	0.900	-	-		OOG6_114949
Panther	1	1.100	-	-	LDO	PTHR46735
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R12004
SonicParanoid	1	1.000	-	-		X4500
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	19	19.250