| Sequence 1: | NP_005177.2 | Gene: | CAPN1 / 823 | HGNCID: | 1476 | Length: | 714 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_610592.1 | Gene: | Pef / 36111 | FlyBaseID: | FBgn0033529 | Length: | 199 | Species: | Drosophila melanogaster |
| Alignment Length: | 225 | Identity: | 50/225 - (22%) |
|---|---|---|---|
| Similarity: | 90/225 - (40%) | Gaps: | 44/225 - (19%) |
- Green bases have known domain annotations that are detailed below.
|
Human 490 PPGEYVVVPSTFEPNKEGDFVLRFFSEKSAGTVELDDQIQANLPDEQVLSEEEIDENFKALFRQL 554
Human 555 AGEDMEISVKELRTILNRIISKHKDLRTKGFSLESCRSMVNLMDRDGNGKLGLVEFNILWNRIRN 619
Human 620 YLSIFRKFDLDKSGSMSAYEMRMAIESAGFKLNKKLYELIITRYSEPD--LAVDFDNFVCCLVRL 682
Human 683 ETMFRFFKTLDTDLDGVVTFDLFKWLQLTM 712 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CAPN1 | NP_005177.2 | Peptidase_C2 | 56..352 | CDD:459889 | |
| Domain III | 355..526 | 6/35 (17%) | |||
| Calpain_III | 364..524 | CDD:238132 | 6/33 (18%) | ||
| Linker | 527..542 | 2/14 (14%) | |||
| Domain IV | 543..713 | 42/172 (24%) | |||
| EFh_PEF_CAPN1 | 546..714 | CDD:320073 | 42/169 (25%) | ||
| EF-hand motif | 546..574 | CDD:320073 | 7/27 (26%) | ||
| EF-hand motif | 589..618 | CDD:320073 | 9/28 (32%) | ||
| EF-hand motif | 619..649 | CDD:320073 | 8/29 (28%) | ||
| EF-hand motif | 655..683 | CDD:320073 | 6/29 (21%) | ||
| EF-hand motif | 685..714 | CDD:320073 | 6/28 (21%) | ||
| Pef | NP_610592.1 | EFh_PEF_peflin | 34..198 | CDD:320059 | 44/188 (23%) |
| EF-hand motif | 34..63 | CDD:320059 | 9/46 (20%) | ||
| EF-hand motif | 71..100 | CDD:320059 | 9/28 (32%) | ||
| EF-hand motif | 101..131 | CDD:320059 | 8/29 (28%) | ||
| EF-hand motif | 137..166 | CDD:320059 | 6/29 (21%) | ||
| EF-hand motif | 167..198 | CDD:320059 | 6/29 (21%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||