DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RLP38 and Fili

DIOPT Version :9

Sequence 1:	NP_188953.1	Gene:	RLP38 / 821887	AraportID:	AT3G23120	Length:	784	Species:	Arabidopsis thaliana
Sequence 2:	NP_001369108.1	Gene:	Fili / 5740472	FlyBaseID:	FBgn0085397	Length:	789	Species:	Drosophila melanogaster

Alignment Length:	459	Identity:	113/459 - (24%)
Similarity:	174/459 - (37%)	Gaps:	96/459 - (20%)

- Green bases have known domain annotations that are detailed below.

plant     3 RSQSYCFLGITITIYFFFCLLPL-PNTFASPPTQSLCRHDQR-------DALLELQKEFPIPSVI 59
            ||:.:....|.:.:.....|:.| |.|.|..|::..|...:.       ||.||     .:|  |
  Fly    12 RSRPWLCGAIPVLLLLLLTLVILPPETTAFCPSKCQCLGGEANSRALCVDAALE-----DVP--I 69

plant    60 LQNPWNKGIDCCSWGGVTCDAILGEVISLKLYFLSTASTSLKSSSALFKLQHLTHLDLSNCNLQG 124
            ..||..|.|:      :|.:.|.....||..|                  ..|..||||...::.
  Fly    70 QLNPETKYIN------LTVNRIRTLEFSLPFY------------------MKLEILDLSQNIIET 110

plant   125 EIPSSIENLSHLTHLDLSTNHLVGEVPASIGNLNQLEYIDLRGNHLRGNIPTSFANLTKLSLLDL 189
            ....:.|..|.|..|:||.|.:......:...|..|..:||..|.:....||:.::|..|..|||
  Fly   111 LGSKNFEYQSELRTLNLSRNLVSSLHKHAFKGLTNLLLLDLSFNRIETVHPTALSDLASLVELDL 175

plant   190 HENNFTG-GDIVLSNLTSLAILDLSSNHFKSFFSADLSGLHNLEQI--------FGNENSFVGLF 245
            ..||... .|.....:.:|.:|...:|......:::|..||.|:.:        |...:||.||.
  Fly   176 TNNNIVSLEDNCFKGMNTLEVLVFRNNRLLDVPASNLWHLHALKSLDMSLNLVEFVRNDSFEGLK 240

plant   246 PASLLKISSLDKIQLSQNQFEGPIDFGNTSSSSRLTMLDISHNNFIGRVPS-SLSKLVNLELLDL 309
            ....|.:......:|..:.|||.|.         |..||:|.|| :..||: .||||.||..|:|
  Fly   241 ELLALSVQGNVMSELDLSAFEGLIS---------LKHLDLSDNN-LTMVPTQQLSKLSNLTYLNL 295

plant   310 SHNNFRGLSPRSISKLVNLTSLDIS----YNKLEGQVPYFIWKPSNLQSVDLSHN---------- 360
            ..|.|..|...:...|.:|..|.:|    ..:::.:.  |: ..::||::.|::|
  Fly   296 GGNRFSQLPAVAFLNLFHLRELHLSRLDFLQRIDSRA--FV-DNTHLQTLHLNNNPQLSDIPMRL 357

plant   361 --------SFFDLGKSVEVVNGA-----KLVGLNLGSNSLQGPIPQWICNFRFVFFLDLSDNRFT 412
                    ..:....|::.:..|     :|..|.||.|.||       ||...::...|....|.
  Fly   358 FQGNPNILEVYMQSNSLQTLYSAQFPVDQLQKLYLGDNPLQ-------CNCSLLWLWRLVTGNFE 415

plant   413 GSIP 416
            |..|
  Fly   416 GVDP 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RLP38	NP_188953.1	PLN00113	11..>721	CDD:331614	111/451 (25%)
		leucine-rich repeat	112..135	CDD:275380	6/22 (27%)
		leucine-rich repeat	136..159	CDD:275380	6/22 (27%)
		leucine-rich repeat	160..183	CDD:275380	7/22 (32%)
		leucine-rich repeat	184..206	CDD:275380	7/22 (32%)
		leucine-rich repeat	207..254	CDD:275380	13/54 (24%)
		leucine-rich repeat	255..276	CDD:275380	5/20 (25%)
		leucine-rich repeat	280..303	CDD:275380	12/23 (52%)
		leucine-rich repeat	304..327	CDD:275380	7/22 (32%)
		leucine-rich repeat	352..376	CDD:275380	6/46 (13%)
		leucine-rich repeat	377..397	CDD:275380	7/19 (37%)
		leucine-rich repeat	401..424	CDD:275380	4/16 (25%)
		leucine-rich repeat	425..448	CDD:275380
		leucine-rich repeat	449..472	CDD:275380
		leucine-rich repeat	473..496	CDD:275380
		leucine-rich repeat	523..545	CDD:275380
		leucine-rich repeat	659..682	CDD:275380
Fili	NP_001369108.1	leucine-rich repeat	75..97	CDD:275378	7/45 (16%)
		leucine-rich repeat	98..121	CDD:275380	6/22 (27%)
		LRR_8	120..180	CDD:404697	19/59 (32%)
		leucine-rich repeat	122..145	CDD:275380	6/22 (27%)
		leucine-rich repeat	146..169	CDD:275380	7/22 (32%)
		LRR	<161..>354	CDD:227223	56/205 (27%)
		leucine-rich repeat	170..193	CDD:275380	7/22 (32%)
		leucine-rich repeat	194..217	CDD:275380	5/22 (23%)
		leucine-rich repeat	218..265	CDD:275380	11/46 (24%)
		leucine-rich repeat	266..289	CDD:275380	12/23 (52%)
		leucine-rich repeat	290..313	CDD:275380	7/22 (32%)
		leucine-rich repeat	314..338	CDD:275380	4/26 (15%)
		LRR_8	337..397	CDD:404697	11/59 (19%)
		leucine-rich repeat	339..360	CDD:275380	4/20 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000