DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CDC48 and TER94

DIOPT Version :9

Sequence 1:	NP_187595.1	Gene:	CDC48 / 820142	AraportID:	AT3G09840	Length:	809	Species:	Arabidopsis thaliana
Sequence 2:	NP_001097249.1	Gene:	TER94 / 36040	FlyBaseID:	FBgn0286784	Length:	826	Species:	Drosophila melanogaster

Alignment Length:	814	Identity:	604/814 - (74%)
Similarity:	699/814 - (85%)	Gaps:	19/814 - (2%)

- Green bases have known domain annotations that are detailed below.

plant     4 PAESSDSKSKKDFSTAILERKKSPNRLVVDEAINDDNSVVSLHPATMEKLQLFRGDTILIKGKKR 68
            |.:|.|  .::|.:||||:||..||||:|:||.|||||||||..|.|::||||||||:::|||:|
  Fly    24 PKDSFD--KREDLATAILKRKDRPNRLIVEEAQNDDNSVVSLSQAKMDELQLFRGDTVILKGKRR 86

plant    69 KDTVCIALADETCEEPKIRMNKVVRSNLRVRLGDVISVHQCPDVKYGKRVHILPVDDTVEGVTGN 133
            |:||||.|:|:||.:.|||||:|||:||.|.|.||:||..||||||||||.|||:|::.||||||
  Fly    87 KETVCIVLSDDTCPDEKIRMNRVVRNNLCVHLSDVVSVQSCPDVKYGKRVRILPIDESTEGVTGN 151

plant   134 LFDAYLKPYFLEAYRPVRKGDLFLVRGGMRSVEFKVIETDPAEYCVVAPDTEIFCEGEPVKREDE 198
            ||:.||||||||||||:..||.|:||..||.:||||:.|||..||:|||:|.|||:|:|:|||:|
  Fly   152 LFEIYLKPYFLEAYRPIHMGDNFIVRAAMRPIEFKVVLTDPEPYCIVAPETVIFCDGDPIKREEE 216

plant   199 ER-LDDVGYDDVGGVRKQMAQIRELVELPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVA 262
            |. |:.|||||:||.|||:|||:|:||||||||.|||:||||||:|||:|||||:||||||||||
  Fly   217 EESLNAVGYDDIGGCRKQLAQIKEMVELPLRHPSLFKAIGVKPPRGILMYGPPGTGKTLIARAVA 281

plant   263 NETGAFFFCINGPEIMSKLAGESESNLRKAFEEAEKNAPSIIFIDEIDSIAPKREKTNGEVERRI 327
            ||||||||.||||||||||||||||||||||||||||:|:||||||||:|||||:||:|||||||
  Fly   282 NETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNSPAIIFIDEIDAIAPKRDKTHGEVERRI 346

plant   328 VSQLLTLMDGLKSRAHVIVMGATNRPNSIDPALRRFGRFDREIDIGVPDEIGRLEVLRIHTKNMK 392
            ||||||||||:|..:|:|||.|||||||||||||||||||||||||:||..||||||||||||||
  Fly   347 VSQLLTLMDGMKKSSHLIVMAATNRPNSIDPALRRFGRFDREIDIGIPDATGRLEVLRIHTKNMK 411

plant   393 LAEDVDLERISKDTHGYVGADLAALCTEAALQCIREKMDVIDLEDDSIDAEILNSMAVTNEHFHT 457
            |.:|||||:|:.::||:||||||:||:|||||.||||||:||||||.||||:|.|:|||.|:|..
  Fly   412 LHDDVDLEQIAAESHGHVGADLASLCSEAALQQIREKMDLIDLEDDKIDAEVLASLAVTMENFRY 476

plant   458 ALGNSNPSALRETVVEVPNVSWNDIGGLENVKRELQETVQYPVEHPEKFEKFGMSPSKGVLFYGP 522
            |:..|:|||||||||||||.:|.||||||:||:||||.||||||||:||.||||.||:|||||||
  Fly   477 AMTKSSPSALRETVVEVPNTTWTDIGGLESVKKELQELVQYPVEHPDKFLKFGMQPSRGVLFYGP 541

plant   523 PGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVREIFDKARQSAPCVLFFDELDSIAT 587
            |||||||||||||||||||||||||||||||||||||||||:||||||.:||||||||||||||.
  Fly   542 PGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVRDIFDKARSAAPCVLFFDELDSIAK 606

plant   588 QRGGGSGGDGGGAADRVLNQLLTEMDGMNAKKTVFIIGATNRPDIIDSALLRPGRLDQLIYIPLP 652
            .| ||:.||.|||||||:||:|||||||.|||.||||||||||||||.|:|||||||||||||||
  Fly   607 AR-GGNVGDAGGAADRVINQILTEMDGMGAKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLP 670

plant   653 DEDSRLNIFKAALRKSPIAKDVDIGALAKYTQGFSGADITEICQRACKYAIRENIEKDIEKEKRR 717
            |:.||..|.||.|||||:||:||:..:||.||||||||:|||||||||.|||:.||.:|.:||.|
  Fly   671 DDKSREAILKANLRKSPLAKEVDLTYIAKVTQGFSGADLTEICQRACKLAIRQAIEAEIRREKER 735

plant   718 SENP-EAMEEDGVDEVSEIKAAHFEESMKYARRSVSDADIRKYQAFAQTLQQSRGFGSEFRFE-- 779
            :||. .||:.|..|.|.||.:|||||:||:|||||||.|||||:.||||||||||||..|||.
  Fly   736 AENQNSAMDMDEDDPVPEITSAHFEEAMKFARRSVSDNDIRKYEMFAQTLQQSRGFGQNFRFPGQ 800

plant   780 --NSAGSGATTGVADPFATSAAAAGD--DDDLYN 809
              |::|||....|..|        ||  |||||:
  Fly   801 TGNTSGSGNNLPVNSP--------GDNGDDDLYS 826

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CDC48	NP_187595.1	CDC48	29..768	CDD:273521	569/740 (77%)
TER94	NP_001097249.1	CDC48	47..787	CDD:273521	569/740 (77%)
		CDC48_N	47..129	CDD:280513	54/81 (67%)
		CDC48_2	153..213	CDD:215011	38/59 (64%)
		AAA	263..392	CDD:278434	114/128 (89%)
		AAA	536..669	CDD:278434	118/133 (89%)
		Vps4_C	<741..783	CDD:286426	27/41 (66%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	252	1.000	Domainoid score	I518
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5168
Inparanoid	1	1.050	1186	1.000	Inparanoid score	I21
OMA	1	1.010	-	-		QHG60945
OrthoDB	1	1.010	-	-		D194195at2759
OrthoFinder	1	1.000	-	-		FOG0000137
OrthoInspector	1	1.000	-	-		otm2966
orthoMCL	1	0.900	-	-		OOG6_100525
Panther	1	1.100	-	-	O	PTHR23077
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1760
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840