Protein Alignment CAMK2G and mek1

DIOPT Version :10

• Sequence 1: NP_001307827.1
• Gene: CAMK2G / 818
• HGNCID: 1463
• Length: 592
• Species: Homo sapiens
• Sequence 2: NP_594908.1
• Gene: mek1 / 2541604
• PomBaseID: SPAC14C4.03
• Length: 445
• Species: Schizosaccharomyces pombe
• Alignment Length: 313
• Identity: 99/313 - (31%)
• Similarity: 159/313 - (50%)
• Gaps: 43/313 - (13%)

Human     9 RFTDDYQLFEE------------LGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSAR----DHQK 57
            ::|.|.....|            ||.|.||.:...:...:..:||.|||:.||:|.:    ||
pombe   143 KYTTDNDFHHEYAGERFNITQRLLGIGGFSRIYMAMDNNTGGQYACKIIDKKKISTKRFFEDH-- 205

Human    58 LEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILE 122
               |..|.|.|.||||::::...:.|...::..::||||:||..:.......|......:.|||:
pombe   206 ---EMTILRKLDHPNIIKVNMEYNSETQFFIFEEMVTGGDLFSYLTKLGTVPEVTTLFIMFQILQ 267

Human   123 SVNHIHQHDIVHRDLKPENLLLASKCKGA-AVKLADFGLAIEVQ-GEQQAWFGFAGTPGYLSPEV 185
            .:.::|:.:|:|||||.||:|:||..... .:.|.|||:|..:| |::.:  .|.|||.|.:||:
pombe   268 GLKYLHEQNIIHRDLKLENILIASSSDTIFRIILTDFGVARCMQKGKRLS--TFVGTPEYTAPEI 330

Human   186 LR-----------KDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWD 239
            .|           ...|||.||:|:.|||:::||.|..|.:.:.       :|....||..|.|.
pombe   331 QRLKGRSQVEKENSSGYGKEVDLWSLGVIMFLLLSGNSPSFADG-------VKEKQVDFRDPVWK 388

Human   240 TVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLR 292
            :|:.:||:||:.:|..||..|.|..|.|.|||..:.|:..:.::....::.|:
pombe   389 SVSRQAKDLISNLLKTNPPDRFTVKQCLSHPWFARHSSRLTKLYETRILKPLK 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAMK2G	NP_001307827.1	STKc_CaMKII	12..303	CDD:270988	98/310 (32%)
		NTF2_like	433..>488	CDD:471850
mek1	NP_594908.1	FHA_MEK1-like	40..143	CDD:438722	99/313 (32%)
		STKc_CAMK	163..420	CDD:270687	92/270 (34%)