Protein Alignment CAMK2G and srk1

DIOPT Version :10

• Sequence 1: NP_001307827.1
• Gene: CAMK2G / 818
• HGNCID: 1463
• Length: 592
• Species: Homo sapiens
• Sequence 2: NP_588136.1
• Gene: srk1 / 2539027
• PomBaseID: SPCC1322.08
• Length: 580
• Species: Schizosaccharomyces pombe
• Alignment Length: 498
• Identity: 141/498 - (28%)
• Similarity: 214/498 - (42%)
• Gaps: 129/498 - (25%)

Human    12 DDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKII-----NTKKLSARDHQKLE-----REARICR 66
            :.|.|.:::|.||||.|.:.:...:.::.|.|::     ||.....|..|.:|     :|.:|.|
pombe   122 EQYTLLQKMGDGAFSNVYKAIHNRTGEKVAIKVVQRAQPNTDPRDPRKRQGVESHNILKEVQIMR 186

Human    67 LLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQH- 130
            .:|||||::|.:.|....::|||.:|..|||||..||...|:||..:.|.|.|:..::.::|:.
pombe   187 RVKHPNIIQLLEFIQTPEYYYLVLELADGGELFHQIVRLTYFSEDLSRHVITQVAHAIRYLHEDC 251

Human   131 DIVHRDLKPENLLLAS---------KCK-----------------GAA----VKLADFGLAIEVQ 165
            .:||||:||||||..|         |.:                 ||.    ::||||||:
pombe   252 GVVHRDIKPENLLFDSIDFVPSRVRKYRAGDDPDKVDEGEFIPGVGAGTIGRIRLADFGLS---- 312

Human   166 GEQQAWFGFAGTP----GYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQI 226
              :..|.....||    ||.:||::|.:.|.|.||:||.|.:||.:|.|:|||:||....|.:::
pombe   313 --KVVWDSHTQTPCGTMGYTAPEIVRDERYSKGVDMWALGCVLYTILCGFPPFYDESISLLTKKV 375

Human   227 KAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECL 291
            ..|.|.|.||.||.::..||:||:.:||::|..|....|.|.|||:
pombe   376 SRGEYSFLSPWWDDISKSAKDLISHLLTVDPESRYDIHQFLAHPWI------------------- 421

Human   292 RKFNARRKLKGAILTTMLVSRNFSVGRQSSAPASPAASAA----------------GLAGQAAKS 340
                                   |..|:.:.||:.|.:.|                ..||.||::
pombe   422 -----------------------SGSREPTFPATDAPNTAQRENPFTYDFLEPEDVAAAGSAART 463

Human   341 LLNKKSDGGVKKRKS----SSSVHLMEPQTTVVHNATDGIKGSTESCNTTTEDEDLKAAPLRTGN 401
                   .||...:.    |.:.|.||.:..    ...|.:|:....|...:.:||........:
pombe   464 -------PGVNSLREVFNISYAAHRMEQEKI----RKRGQRGNQGIMNFMGDMDDLMEENDDYDD 517

Human   402 GSSVPEGRSSR----DRTAPS-AGMQPQPSLCSSAMRKQEIIK 439
            |:...|....|    ....|| |..||..|...|:.|.:...|
pombe   518 GTKSVEHSMKRVNLSGENDPSLASRQPAQSQQQSSQRSRNKFK 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAMK2G	NP_001307827.1	STKc_CaMKII	12..303	CDD:270988	108/335 (32%)
		NTF2_like	433..>488	CDD:471850	2/7 (29%)
srk1	NP_588136.1	STKc_RCK1-like	122..421	CDD:270998	107/304 (35%)