Protein Alignment CAMK2G and camk2g

DIOPT Version :10

• Sequence 1: NP_001307827.1
• Gene: CAMK2G / 818
• HGNCID: 1463
• Length: 592
• Species: Homo sapiens
• Sequence 2: XP_012821441.1
• Gene: camk2g / 100135711
• XenbaseID: XB-GENE-868520
• Length: 654
• Species: Xenopus tropicalis
• Alignment Length: 578
• Identity: 444/578 - (76%)
• Similarity: 458/578 - (79%)
• Gaps: 91/578 - (15%)

Human     1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARIC 65
            ||||||||||||:|||:|||||||||||||||||:|.||||||||||||||||||||||||||||
 Frog     1 MATTATCTRFTDEYQLYEELGKGAFSVVRRCVKKSSNQEYAAKIINTKKLSARDHQKLEREARIC 65

Human    66 RLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQH 130
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog    66 RLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQH 130

Human   131 DIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPV 195
            ||||||||||||||||||||||||||||||||||||:||||||||||||||||||||||||||||
 Frog   131 DIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPV 195

Human   196 DIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKR 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   196 DIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKR 260

Human   261 ITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFS---------- 315
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   261 ITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSGIAFGCRKAA 325

Human   316 ---------------VGRQSSAPASPAASAAGLAGQAAKSLLNKKSDGGVKKRKSSSSVHL---- 361
                           ||||:|||...|.|||.|..||||||||||:| |||||||||||||
 Frog   326 STVPCTSSTGDTITGVGRQTSAPVVAATSAANLVEQAAKSLLNKKTD-GVKKRKSSSSVHLMPQT 389

Human   362 -------------------MEPQTTVVHNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSSVPE 407
                               |||||||||||||||||||||||||||||||||.|...|:|..:.:
 Frog   390 NNKNSIISPAKENPPLQTSMEPQTTVVHNATDGIKGSTESCNTTTEDEDLKANPFCPGDGPLLLQ 454

Human   408 GRSSRDRTAPSAGMQPQPSLC------------------------------------------SS 430
            |.|..:....:..:..|..||                                          ||
 Frog   455 GWSQSESKIQTESLHSQIGLCGSSTAQSCEEKLLAWDSPGQTVELEPAQSEPMLTPVVPFSLSSS 519

Human   431 AMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFEN 488
            .:||||||||||||||||||||||||||||||||||||||||||||||||||||||:|
 Frog   520 LLRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFDN 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAMK2G	NP_001307827.1	STKc_CaMKII	12..303	CDD:270988	285/290 (98%)
		NTF2_like	433..>488	CDD:471850	54/54 (100%)
camk2g	XP_012821441.1	STKc_CaMKII	12..303	CDD:270988	285/290 (98%)
		CaMKII_AD	522..649	CDD:285524	55/56 (98%)