Protein Alignment CAMK2D and CaMKI

DIOPT Version :9

• Sequence 1: NP_001308498.1
• Gene: CAMK2D / 817
• HGNCID: 1462
• Length: 533
• Species: Homo sapiens
• Sequence 2: NP_524622.1
• Gene: CaMKI / 43792
• FlyBaseID: FBgn0016126
• Length: 405
• Species: Drosophila melanogaster
• Alignment Length: 396
• Identity: 147/396 - (37%)
• Similarity: 204/396 - (51%)
• Gaps: 50/396 - (12%)

Human    12 DEYQLFEELGKGAFSVVRRC-MKIPTGQEYAAKIINTKKLSARDHQKLEREARICR--------- 66
            ::|.|...||.||||.||.. .|...|:.:|.|||:.|.|..:: :.||.|.|:.|
  Fly    29 EKYNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIIDKKALKGKE-ESLENEIRVLRRFSANHFDG 92

Human    67 ------LLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVN 125
                  .|.|||||:|.::..::...|||.:||||||||:.||.:..|:|.||||.|:||||:|:
  Fly    93 KCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGELFDRIVEKGSYTEKDASHLIRQILEAVD 157

Human   126 HCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLA-IEVQGDQQAWFGFAGTPGYLSPEVLRKD 189
            :.|..|:|||||||||||..|....:.:.::||||: :|..|....   ..|||||::||||.:.
  Fly   158 YMHEQGVVHRDLKPENLLYYSPDDDSKIMISDFGLSKMEDSGIMAT---ACGTPGYVAPEVLAQK 219

Human   190 PYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLT 254
            ||||.||:|:.|||.||||.|||||:||:...|:.||..|.::|.||.||.::..||..|..::.
  Fly   220 PYGKAVDVWSIGVISYILLCGYPPFYDENDANLFAQILKGDFEFDSPYWDEISESAKHFIKNLMC 284

Human   255 INPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSAAKS 319
            :...||.|..:||.|.||......:..:|...:....|.|...|..:.....|::......|..|
  Fly   285 VTVEKRYTCKQALGHAWISGNEASSRNIHGTVSEQLKKNFAKSRWKQAYYAATVIRQMQRMALNS 349

Human   320 LLKKPDGVKINNKANVVTSPKEN----IPTPALEPQTTVIHNPDGNKESTESSNTTIEDEDVKAR 380
                      |:.||..:|...|    .||.|....|               ||.....:.|::.
  Fly   350 ----------NSNANFDSSNSSNQDSTTPTAATGAWT---------------SNVLSSQQSVQSH 389

Human   381 KQEIIK 386
            .||:.|
  Fly   390 AQEMNK 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAMK2D	NP_001308498.1	STKc_CaMKII	12..303	CDD:270988	129/307 (42%)
		CaMKII_AD	380..507	CDD:285524	3/7 (43%)
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	123/275 (45%)
		S_TKc	31..302	CDD:214567	123/274 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X46
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.920