Protein Alignment CAMK2D and camk2d2

DIOPT Version :10

• Sequence 1: NP_001308498.1
• Gene: CAMK2D / 817
• HGNCID: 1462
• Length: 533
• Species: Homo sapiens
• Sequence 2: XP_009304932.1
• Gene: camk2d2 / 436815
• ZFINID: ZDB-GENE-040718-277
• Length: 554
• Species: Danio rerio
• Alignment Length: 551
• Identity: 470/551 - (85%)
• Similarity: 494/551 - (89%)
• Gaps: 43/551 - (7%)

Human     5 TTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLK 69
            |.|||||||||||||||||||||||||:||.:|||||||||||||||||||||||||||||||||
Zfish     4 TICTRFTDEYQLFEELGKGAFSVVRRCVKISSGQEYAAKIINTKKLSARDHQKLEREARICRLLK 68

Human    70 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVH 134
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||:|||:|||||
Zfish    69 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHVNGIVH 133

Human   135 RDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWA 199
            |||||||||||||.|||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish   134 RDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWA 198

Human   200 CGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITAS 264
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||:|||||:
Zfish   199 CGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAA 263

Human   265 EALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSAAKSLL-KKPDGVK 328
            ||||||||||||||||||||||||:||||||||||||||||||:|.||||||||||| |||||||
Zfish   264 EALKHPWICQRSTVASMMHRQETVECLKKFNARRKLKGAILTTLLVTRNFSAAKSLLNKKPDGVK 328

Human   329 INNKANVVTSPKENIPTPALEPQTTVIHNP-DGNKESTESSNTTIEDEDV--------------- 377
            :|||.|:.:|||:..|.||||||||||||| |.|||||||:||||||||:
Zfish   329 VNNKTNLASSPKDTGPAPALEPQTTVIHNPVDRNKESTESANTTIEDEDLKARRFGNLSINSIWQ 393

Human   378 --------------------------KARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEP 416
                                      ||||||||||||||||:|||||||||.||||||||:|||
Zfish   394 PSVGRPQNSEPKQAPNSSVQTCQVINKARKQEIIKVTEQLIESINNGDFEAYAKICDPGLTSFEP 458

Human   417 EALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTM 481
            |||||||||.|||||||||||||.|||:|||:|||||||:|:||||||||||||||||||||:||
Zfish   459 EALGNLVEGHDFHRFYFENALSKGNKPVHTILLNPHVHLIGEDAACIAYIRLTQYMDGSGMPRTM 523

Human   482 QSEETRVWHRRDGKWQNVHFHRSGSPTVPIK 512
            |||||||||||||||.|:||||||:|:||||
Zfish   524 QSEETRVWHRRDGKWLNIHFHRSGAPSVPIK 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAMK2D	NP_001308498.1	STKc_CaMKII	12..303	CDD:270988	281/290 (97%)
		CaMKII_AD	380..507	CDD:285524	114/126 (90%)
camk2d2	XP_009304932.1	STKc_CaMKII	11..302	CDD:270988	281/290 (97%)
		CaMKII_AD	422..549	CDD:285524	114/126 (90%)