Protein Alignment CAMK2D and CG17528

DIOPT Version :10

• Sequence 1: NP_001308498.1
• Gene: CAMK2D / 817
• HGNCID: 1462
• Length: 533
• Species: Homo sapiens
• Sequence 2: NP_001036462.1
• Gene: CG17528 / 3355134
• FlyBaseID: FBgn0261387
• Length: 748
• Species: Drosophila melanogaster
• Alignment Length: 262
• Identity: 103/262 - (39%)
• Similarity: 149/262 - (56%)
• Gaps: 8/262 - (3%)

Human    14 YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHD 78
            |.|...:|.|.|::|.:.....||..||.|||:..|...::|. ::.|.|:.:.|.||:|:.|..
  Fly   477 YSLGRIIGDGNFAIVFKIKHRQTGHSYALKIIDKNKCKGKEHY-IDAEVRVMKKLNHPHIISLIL 540

Human    79 SISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLL 143
            |:.:....|||.:.|:||:||:.|.....:||..:...|:.:..::.:.|..||||||:||||||
  Fly   541 SVDQNTNMYLVLEYVSGGDLFDAITQVTRFSENQSRIMIRHLGAAMTYLHSMGIVHRDIKPENLL 605

Human   144 LASKSKG--AAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYI 206
            :.....|  ..:||||||||.||   ....:...|||.|::||:|.:..||..:|:||.|:||||
  Fly   606 VKLDEHGNVLELKLADFGLACEV---NDLLYAVCGTPTYVAPEILLEVGYGLKIDVWAAGIILYI 667

Human   207 LLVGYPPFW--DEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKH 269
            ||.|:|||.  |..|..|:..|.:|.|:||.|.|..:....:|||..||..:|..|.|:.:.|.|
  Fly   668 LLCGFPPFVAPDNQQEPLFDAIISGIYEFPDPYWSDIGDGVRDLIANMLQADPDVRFTSEDILDH 732

Human   270 PW 271
            .|
  Fly   733 SW 734

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAMK2D	NP_001308498.1	STKc_CaMKII	12..303	CDD:270988	103/262 (39%)
		CaMKII_AD	380..507	CDD:285524
CG17528	NP_001036462.1	DCX1	156..239	CDD:340526
		Ubl1_cv_Nsp3_N-like	309..392	CDD:475130
		Protein Kinases, catalytic domain	477..734	CDD:473864	102/260 (39%)