Protein Alignment CAMK2D and cmk1

DIOPT Version :10

• Sequence 1: NP_001308498.1
• Gene: CAMK2D / 817
• HGNCID: 1462
• Length: 533
• Species: Homo sapiens
• Sequence 2: NP_593464.1
• Gene: cmk1 / 2542442
• PomBaseID: SPACUNK12.02C
• Length: 335
• Species: Schizosaccharomyces pombe
• Alignment Length: 314
• Identity: 126/314 - (40%)
• Similarity: 179/314 - (57%)
• Gaps: 12/314 - (3%)

Human    13 EYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLL--KHPNIVR 75
            :|::...||.|.::.||..:.|.|.:.|||||:| ||:..:....::.|..|.:.:  :||||:.
pombe    30 KYRVGRVLGGGTYATVREAVHIETNKMYAAKIMN-KKMMEKKQDFVKNEIAILKRVSYEHPNILH 93

Human    76 LHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPE 140
            |.|........||:.:|.||||||:.|.|:..:.||||:..::....:|.:.|.|||||||||||
pombe    94 LVDFFETVNNLYLITELATGGELFDRICAKGSFYEADAAALMRTTTSAVKYLHDNGIVHRDLKPE 158

Human   141 NLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFA-GTPGYLSPEVLRKDPYGKPVDMWACGVIL 204
            |||..||...:.:.:|||||:...:..|......| |||.|::|||.|:..|||||||||.|||.
pombe   159 NLLYRSKDPNSDLLIADFGLSHFYEDSQYYMLMTACGTPEYMAPEVFRRTGYGKPVDMWAIGVIT 223

Human   205 YILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKH 269
            |.||.||.||....|..:.:.|.|..|.|..|.|..::..|||.|.|.|..:|:||:||::||||
pombe   224 YFLLSGYTPFARPSQVEVIEAILANEYTFNDPCWSGISETAKDFIKKCLENDPSKRLTAADALKH 288

Human   270 PWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSAAKSLLKK 323
            |::.::....|.:    ..:..:.||||:..:    |...|.|.|:..|.|..|
pombe   289 PFLSEKRPATSNL----LPNVRENFNARKTFR----TAYNAVRAFNTWKKLENK 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAMK2D	NP_001308498.1	STKc_CaMKII	12..303	CDD:270988	119/292 (41%)
		CaMKII_AD	380..507	CDD:285524
cmk1	NP_593464.1	STKc_CAMK	30..290	CDD:270687	113/260 (43%)