Protein Alignment CAMK2D and Camk2d

DIOPT Version :10

• Sequence 1: NP_001308498.1
• Gene: CAMK2D / 817
• HGNCID: 1462
• Length: 533
• Species: Homo sapiens
• Sequence 2: NP_036651.1
• Gene: Camk2d / 24246
• RGDID: 2263
• Length: 533
• Species: Rattus norvegicus
• Alignment Length: 533
• Identity: 529/533 - (99%)
• Similarity: 531/533 - (99%)
• Gaps: 0/533 - (0%)

Human     1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARIC 65
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat     1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARIC 65

Human    66 RLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLN 130
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat    66 RLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLN 130

Human   131 GIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPV 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   131 GIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPV 195

Human   196 DMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKR 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   196 DMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKR 260

Human   261 ITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSAAKSLLKKPD 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   261 ITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSAAKSLLKKPD 325

Human   326 GVKINNKANVVTSPKENIPTPALEPQTTVIHNPDGNKESTESSNTTIEDEDVKARKQEIIKVTEQ 390
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   326 GVKINNKANVVTSPKENIPTPALEPQTTVIHNPDGNKESTESSNTTIEDEDVKARKQEIIKVTEQ 390

Human   391 LIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHL 455
            |||||||||||||||||||||||||||||||||||||||||||||||.|.|||||||||||||||
  Rat   391 LIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALPKINKPIHTIILNPHVHL 455

Human   456 VGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIKPPCIPNGK 520
            |||||||||||||||||||:|||||||||||||||||||||||:|||||||||||||||||||||
  Rat   456 VGDDAACIAYIRLTQYMDGNGMPKTMQSEETRVWHRRDGKWQNIHFHRSGSPTVPIKPPCIPNGK 520

Human   521 ENFSGGTSLWQNI 533
            |||||||||||||
  Rat   521 ENFSGGTSLWQNI 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAMK2D	NP_001308498.1	STKc_CaMKII	12..303	CDD:270988	290/290 (100%)
		CaMKII_AD	380..507	CDD:285524	122/126 (97%)
Camk2d	NP_036651.1	STKc_CaMKII	12..303	CDD:270988	290/290 (100%)
		Autoinhibitory domain. /evidence=ECO:0000250	283..292		8/8 (100%)
		Calmodulin-binding. /evidence=ECO:0000250	291..301		9/9 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	337..375		37/37 (100%)
		CaMKII_AD	380..507	CDD:285524	122/126 (97%)