Protein Alignment CAMK2D and camk2d

DIOPT Version :10

• Sequence 1: NP_001308498.1
• Gene: CAMK2D / 817
• HGNCID: 1462
• Length: 533
• Species: Homo sapiens
• Sequence 2: XP_017952440.2
• Gene: camk2d / 100135023
• XenbaseID: XB-GENE-868293
• Length: 537
• Species: Xenopus tropicalis
• Alignment Length: 539
• Identity: 491/539 - (91%)
• Similarity: 503/539 - (93%)
• Gaps: 32/539 - (5%)

Human     1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARIC 65
            ||| ||||||||||||||||||||||||||||||.||||||||||||||||||||||||||||||
 Frog     1 MAS-TTCTRFTDEYQLFEELGKGAFSVVRRCMKITTGQEYAAKIINTKKLSARDHQKLEREARIC 64

Human    66 RLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLN 130
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog    65 RLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLN 129

Human   131 GIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPV 195
            |||||||||||||||||.|||||||||||||||||||||||||||||||||||||||||||||||
 Frog   130 GIVHRDLKPENLLLASKLKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPV 194

Human   196 DMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKR 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   195 DMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKR 259

Human   261 ITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSAAKSLLKKPD 325
            |||:|||:|||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   260 ITAAEALRHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSAAKSLLKKPD 324

Human   326 GVKINNKANVVTSPKENIPTPALEPQTTVIHNP-DGNKESTESSNTTIEDEDVKA---------- 379
            ||||||||||:||||:  |||.||||:|||||| |||||||||||||||||||||
 Frog   325 GVKINNKANVITSPKD--PTPPLEPQSTVIHNPADGNKESTESSNTTIEDEDVKATKCTENTYSK 387

Human   380 ------------------RKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGM 426
                              |||||||||||||||||||||||||||||||||:|||||||||||||
 Frog   388 THLHESEPSRNSSSSVQSRKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGM 452

Human   427 DFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHR 491
            |||||||||||||||||:|||||||||||:|:|||||||||||||:|.:||||||||||||||||
 Frog   453 DFHRFYFENALSKSNKPVHTIILNPHVHLIGEDAACIAYIRLTQYLDSTGMPKTMQSEETRVWHR 517

Human   492 RDGKWQNVHFHRSGSPTVP 510
            |||||||||||||||||:|
 Frog   518 RDGKWQNVHFHRSGSPTIP 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAMK2D	NP_001308498.1	STKc_CaMKII	12..303	CDD:270988	286/290 (99%)
		CaMKII_AD	380..507	CDD:285524	119/126 (94%)
camk2d	XP_017952440.2	STKc_CaMKII	11..302	CDD:270988	286/290 (99%)
		CaMKII_AD	406..533	CDD:285524	119/126 (94%)