DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment AT2G20650 and TUL1

DIOPT Version :9

Sequence 1:	NP_179657.2	Gene:	AT2G20650 / 816593	AraportID:	AT2G20650	Length:	559	Species:	Arabidopsis thaliana
Sequence 2:	NP_012890.1	Gene:	TUL1 / 853832	SGDID:	S000001517	Length:	758	Species:	Saccharomyces cerevisiae

Alignment Length:	585	Identity:	149/585 - (25%)
Similarity:	232/585 - (39%)	Gaps:	185/585 - (31%)

- Green bases have known domain annotations that are detailed below.

plant    75 TVNSSSKF-------------PDFRKESGNSVIELV------TSPTKITGVHYVQGAVVFHDVFD 120
            :::.||||             .|:.::..|.|.|||      |..|.:..:..||      |.::
Yeast   257 SISQSSKFHSLFALPHYMSFQNDYNEKIFNDVKELVDEFWNFTDYTDVMTMKDVQ------DAYN 315

plant   121 NEHNVGGAQIKVEGVYIWPFRQLRLVANSGKKSDSGLEDDYL---LSNPYHLLGIFSSQVFQESP 182
            |      |..|.|.:.   |.||. ..|...:....|.||.|   |..|.:|..:
Yeast   316 N------ANFKCEYLI---FLQLE-PWNQYTRDQIKLIDDELNWPLGRPANLSSL---------- 360

plant   183 RDRILKQKTSPIYEMEKHCNIEIAAQISQSTSSENNGDKDRYQIEGLMESPAVDDEVDCFSPLSL 247
                     .||       |:                      :.||:.||      ||...|.|
Yeast   361 ---------PPI-------NV----------------------VSGLLYSP------DCGVRLGL 381

plant   248 NATSINVEVYYNKAVNYTLMVTFVS----------FLQVLLLIRQMEHSNTQSGAAKVSIVMIGQ 302
            :    ||     |...|.|.:..:.          ..|:.||:.||.|:||.|...|:|......
Yeast   382 H----NV-----KGTRYELKIMSIRKHLLFGIALFAAQIYLLLTQMHHTNTPSMVNKISFYCFSM 437

plant   303 QAIMDSYLCLLHLTAGILVESLFNAFATAAFFKFVVFSIFEMRYLLSIWKATRPSTSGEG----- 362
            ..::|..|..|:..|..:|..|:.....:||..|::.||||:|||:||: |::.:....|
Yeast   438 INLVDGSLATLYFVAASVVPELYLPLVISAFSCFILASIFEIRYLISIY-ASQVNEQNVGIINLL 501

plant   363 ------WETMRRELSF----------LYSRFYGILLGGILLMYEFHNYMRP--------ILLLMY 403
                  ::..|...:|          ||.||:.:|:....|:....::.|.        ::.::.
Yeast   502 RGNTGTYDENRPRPAFIPDEGSIGGSLYGRFFFMLIIFTFLILSSTSWPRQLRMVFEYILIFILN 566

plant   404 SFWIPQIVANVVR------------------DSRKPLHPYYILGMTVTRLAIPLYVFGCPKNFMR 450
            |:|||||..|.|:                  .::.||...:::|.|:.|....:|||....|..|
Yeast   567 SYWIPQIFRNAVKGIPSRRERARSSIGGNRSQNKMPLLWSFVIGTTIIRSLPVVYVFTYSSNVFR 631

plant   451 VEPSKAWCVSLCAFMGFQAGVLLLQHYFGSRCFVPRKLLPEKYSYYRRL-------------DHN 502
            ......:.|.|..::.||..:|..|...|||.|:|:..:|:.|||::.|             :|.
Yeast   632 HHKDVHFVVFLSLWLLFQISILYSQDVLGSRWFLPKHTIPDGYSYFKPLSNEYISEHGGGTAEHT 696

plant   503 VNRSRDCVICMTTIDL-------RHRI--NDCMVTPCEHIFHSGCLQRWMDIKMECPTCRRPLPP 558
            |    ||.|||:.:.:       .|::  :..|||||.|:||:.||:.||:.|::||.||.||||
Yeast   697 V----DCAICMSDVPIYIEEIPETHKVDQHSYMVTPCNHVFHTSCLENWMNYKLQCPVCRSPLPP 757

plant 559 558
Yeast 758 757

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AT2G20650	NP_179657.2	DUF2921	<405..483	CDD:402626	26/95 (27%)
AT2G20650	NP_179657.2	COG5540	<508..558	CDD:227827	25/58 (43%)
TUL1	NP_012890.1	COG5540	320..758	CDD:227827	132/510 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	60	1.000	Domainoid score	I2693
eggNOG	1	0.900	-	-		E1_COG5540
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	158	1.000	Inparanoid score	I1110
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0014593
OrthoInspector	1	1.000	-	-		otm7768
orthoMCL	1	0.900	-	-		OOG6_105468
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11848
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.760