Protein Alignment ACSBG2 and pcs60

DIOPT Version :10

• Sequence 1: NP_112186.3
• Gene: ACSBG2 / 81616
• HGNCID: 24174
• Length: 666
• Species: Homo sapiens
• Sequence 2: NP_001342732.1
• Gene: pcs60 / 2539253
• PomBaseID: SPCC1827.03C
• Length: 512
• Species: Schizosaccharomyces pombe
• Alignment Length: 510
• Identity: 99/510 - (19%)
• Similarity: 187/510 - (36%)
• Gaps: 149/510 - (29%)

Human    81 LNFNQYYEACRKAAKSLIKLGLERFHGVGILGFNSAEWFITAVGAILAGGLCVGIYATNSAEVCQ 145
            |:|::...|.....:.:..||::....|.|...|..|:.:..........:|..:.:.......:
pombe    28 LSFSELRIAIMDLQRQIASLGIKVGDPVNIAIPNGLEFVVAFYAVSWQRAICGPLNSNYKQSEFE 92

Human   146 YVITHAKVNILLVENDQQLQKILSIPQSSLEPLKAIIQYRLPMKKNNNLYSWDDFMELGRSIPDT 210
            :.|            |....|::.:|:.|:......::....:.......:|         .|.:
pombe    93 FYI------------DDLKSKLVIVPEGSVAANTPAVRAAKKLSVAVAELAW---------CPKS 136

Human   211 QLEQVI--ESQKAN-----------QCAVLIYTSGTTGIPKGVMLSHDNITWIAGAVTKDFKLTD 262
            :|.:::  |..|.|           ...::::||||||.||.|.|:|.|:......:|..::| |
pombe   137 RLVRIVHFEGAKINAPQPLGLPQPDDVMLVLHTSGTTGRPKVVPLTHKNLCRSIHNITTSYRL-D 200

Human   263 KHETVVSYLPLSHIAAQMMDIW----------VPIKIGALTY---FAQADALKGTLVSTLKEV-- 312
            ..:|....:||.|:...:..:.          ||.|..|.::   |.|..|...|.|.|:.::
pombe   201 PRDTSYVVMPLFHVHGLLCGLLSTLASGGCAVVPPKFSAHSFWKEFIQYGATWYTAVPTIHQILL 265

Human   313 -----KPTVFIGVPQIWEKIHEMVKKNSAKSMGLKKKAFVWARNIGFKVNSKKMLGKYNTPVSYR 372
                 ||     :|:|                                    :.:...::|::
pombe   266 RTPPPKP-----LPRI------------------------------------RFIRSCSSPLA-- 287

Human   373 MAKTLVFSKVKTSLGLDHCHSFISGTAPLNQETAEFFLSLDIPIGELYGLSESS----------- 426
               ..|.||::.                          :...|:.|.|.::|:|
pombe   288 ---PPVLSKLEA--------------------------TFRAPVLEAYAMTEASHQMTTNPLPPL 323

Human   427 --GPHTISNQNNYRLLSCGKILTGCKNMLFQQNKDGIGEICLWGRHIFMGYLESETETTEAIDDE 489
              .||::.......|    |||....|.: .|.|:  ||||:.|.::..|||.:......:...:
pombe   324 VHKPHSVGKPFGVEL----KILDQKGNEM-PQGKE--GEICVRGINVTKGYLNNPAANKSSFTKD 381

Human   490 GWLHSGDLGQLDGLGFLYVTGHIKEILITAGGENVPPIPVETLVKKKIPIISNAM 544
            .:..:||.|:||..|::::||.||| |:..|||.:.|..::.::.:. |.:|.|:
pombe   382 RFFRTGDEGKLDKDGYVFITGRIKE-LVNRGGEKISPAEIDAVLMQH-PDVSEAV 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACSBG2	NP_112186.3	ACSBG_like	73..665	CDD:341256	99/510 (19%)
pcs60	NP_001342732.1	FACL_fum10p_like	14..502	CDD:341249	99/510 (19%)