Protein Alignment ACSBG2 and acs-18

DIOPT Version :10

• Sequence 1: NP_112186.3
• Gene: ACSBG2 / 81616
• HGNCID: 24174
• Length: 666
• Species: Homo sapiens
• Sequence 2: NP_501893.1
• Gene: acs-18 / 177918
• WormBaseID: WBGene00011173
• Length: 700
• Species: Caenorhabditis elegans
• Alignment Length: 634
• Identity: 155/634 - (24%)
• Similarity: 282/634 - (44%)
• Gaps: 93/634 - (14%)

Human    73 KNGK-KWEILNFNQYYEACRKAAKSLIKLGLE--RFHGVGILGFNSAEWFITAVGAILAGGLCVG 134
            |:|| :||.::::|.:|....|::::.|||:|  ....:||...|..||.::.:.......:.|.
 Worm   106 KDGKLEWEWISYDQAFETSDHASQAIRKLGIEIGEESKIGIYSNNRPEWILSEMAIHNFSNVSVP 170

Human   135 IYATNSAEVCQYVITHAKVNILLVENDQQLQKILSIPQSSLEPLKAIIQYR------LPMKKNNN 193
            :|.|.:.:...|:....:::::.|:.:.:.::::. .:|.|..||.|:|:.      ..|.:.|:
 Worm   171 LYDTITNDDMHYITNLCEISLMFVDAEIKTKQLIR-DKSYLSSLKYIVQFNECSDDIKEMAREND 234

Human   194 --LYSWDDFMELGRS------IPDTQLEQVIESQKANQCAVLIYTSGTTGIPKGVMLSHDNITWI 250
              |:|:::|:|:|:.      :|.|          ....|.:.:||||||.||||||:|.|:...
 Worm   235 FRLWSFNEFVEMGKKQKHRPHVPPT----------PETLATISFTSGTTGRPKGVMLTHLNMCSA 289

Human   251 AGAVTKDFKLTDKHETVVSYLPLSHIAAQMMDIWVPIKIGALTYFAQADALKGTLVSTLKEVKPT 315
            ..:..:........:..:|||||:||..::. :.....||:...|::.|  ...||..::.:.|.
 Worm   290 TMSCEEFENEAGVQDAYLSYLPLAHIYERLC-LLSNFMIGSRIGFSRGD--PKLLVDDVQALAPR 351

Human   316 VFIGVPQIWEKIHEMVKKNSAKSMGLKKKAFVWARNIGFKVNSKKMLGKYNTPVSYRMAKT---- 376
            .|..||::.:|||:.|.| ..:...|||  .:....|.:|:...||.||       ...||
 Worm   352 SFATVPRVIDKIHKAVMK-QVQDKPLKK--MILNAAIAYKLYHYKMTGK-------ATRKTWVDK 406

Human   377 LVFSKVKTSLGLDHCHSFISGTAPLNQETAEFFL-SLDIPIGELYGLSESSGPHTISNQNNYRL- 439
            .|..|::..|| .:....|.|.|..:.....|.. :..:.:.|.||.:|:|||.|:....:.|:
 Worm   407 YVLHKIQMLLG-PNIRQLILGAAKSDVSAMRFARGAFGVEVLEGYGQTETSGPTTLQLVGDTRIG 470

Human   440 -----LSCGKI-LTGCKNMLFQQNKDGIGEICLWGRHIFMGYLESETETTEAIDDEGWLHSGDLG 498
                 ::|..| |.....:.:..:|:| ||:.:.|.::..||.::...|..:..::|::.:||:|
 Worm   471 CVGPPMACAMIKLIDVPELGYSVDKNG-GEVLVKGHNVTSGYYKNPEATASSFTEDGYMKTGDIG 534

Human   499 QLDGLGFLYVTGHIKEILITAGGENVPPIPVETLVKKKIPIISNAMLVGDKLK------------ 551
            :....|.|.:....|.:.....|:.|.|...|:|.... ..:....:.||..|
 Worm   535 RFTAEGSLQIIDRRKNVFKMPQGKFVAPDLTESLYTSS-SFVQQIYVHGDMEKPWLVAIVVPDPE 598

Human   552 FLSMLLTLKCEMNQMSGEPLDKLNFEAINFCRGLGSQASTVTEIVKQQDPLVYKAIQQGINAVNQ 616
            :|:.....|..:|..:.|.|..:...|.:..|    |...:||..|       :...:|:..|:
 Worm   599 YLASYALTKHNINGKTYEQLCNIPILADDVLR----QFVELTEEDK-------RPRYEGVYGVH- 651

Human   617 EAMNNAQRIEKWVILEKDFSIYGGELGPMMKLKRHFVAQKYKKQIDHMY 665
                         :....||...|...|.:|.||:.:||.:|.:||.||
 Worm   652 -------------LTPVAFSAENGLTTPTLKNKRNAIAQFFKAEIDGMY 687

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACSBG2	NP_112186.3	ACSBG_like	73..665	CDD:341256	153/632 (24%)
acs-18	NP_501893.1	LC-FACS_euk	111..688	CDD:341250	152/629 (24%)