Protein Alignment CAMK2B and CG17528

DIOPT Version :10

• Sequence 1: XP_011513849.1
• Gene: CAMK2B / 816
• HGNCID: 1461
• Length: 709
• Species: Homo sapiens
• Sequence 2: NP_001036462.1
• Gene: CG17528 / 3355134
• FlyBaseID: FBgn0261387
• Length: 748
• Species: Drosophila melanogaster
• Alignment Length: 262
• Identity: 104/262 - (39%)
• Similarity: 150/262 - (57%)
• Gaps: 8/262 - (3%)

Human    14 YQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHD 78
            |.|...||.|.|::|.:.....|||.||.|||:..|...::|. ::.|.|:.:.|.|.:|:.|..
  Fly   477 YSLGRIIGDGNFAIVFKIKHRQTGHSYALKIIDKNKCKGKEHY-IDAEVRVMKKLNHPHIISLIL 540

Human    79 SISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLL 143
            |:.:....|||.:.|:||:||:.|.....:||..:...|:.:..|:.:.|.||:||||:||||||
  Fly   541 SVDQNTNMYLVLEYVSGGDLFDAITQVTRFSENQSRIMIRHLGAAMTYLHSMGIVHRDIKPENLL 605

Human   144 LASKCKG--AAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYI 206
            :.....|  ..:||||||||.||   ....:...|||.|::||:|.:..||..:|:||.|:||||
  Fly   606 VKLDEHGNVLELKLADFGLACEV---NDLLYAVCGTPTYVAPEILLEVGYGLKIDVWAAGIILYI 667

Human   207 LLVGYPPFW--DEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKH 269
            ||.|:|||.  |..|..|:..|.:|.|:||.|.|..:....::||..||..:|..|.|:.:.|.|
  Fly   668 LLCGFPPFVAPDNQQEPLFDAIISGIYEFPDPYWSDIGDGVRDLIANMLQADPDVRFTSEDILDH 732

Human   270 PW 271
            .|
  Fly   733 SW 734

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAMK2B	XP_011513849.1	STKc_CaMKII	12..303	CDD:270988	104/262 (40%)
		CaMKII_AD	577..704	CDD:285524
CG17528	NP_001036462.1	DCX1	156..239	CDD:340526
		Ubl1_cv_Nsp3_N-like	309..392	CDD:475130
		Protein Kinases, catalytic domain	477..734	CDD:473864	103/260 (40%)