Protein Alignment PLA2G12A and GXIVsPLA2

DIOPT Version :10

• Sequence 1: NP_110448.2
• Gene: PLA2G12A / 81579
• HGNCID: 18554
• Length: 189
• Species: Homo sapiens
• Sequence 2: NP_648815.1
• Gene: GXIVsPLA2 / 39734
• FlyBaseID: FBgn0036545
• Length: 230
• Species: Drosophila melanogaster
• Alignment Length: 149
• Identity: 52/149 - (34%)
• Similarity: 81/149 - (54%)
• Gaps: 21/149 - (14%)

Human    42 VHKIDTYLNAALDLLGGEDGLCQYKC--SDGSKPFPR----YGYKPSPPNGCGSPLFGVHLNIG- 99
            ||::   .:||:|    |:  |.|:|  .|...|.||    ..|.|: .:||||  .|:.::..
  Fly    59 VHEV---FDAAVD----EN--CIYQCPAPDIGGPAPRAVQNKFYTPT-ADGCGS--LGLRISTDY 111

Human   100 IPS--LTKCCNQHDRCYETCGKSKNDCDEEFQYCLSKICRDVQKTLGLTQHVQACETTVELLFDS 162
            :|:  :..|||.||.||:||...|..||.:|:.||.|.|...:|::.....::.|:...::||..
  Fly   112 LPAKEMETCCNDHDICYDTCNSDKELCDLDFKRCLYKYCDSYEKSIASDLMMKGCKAAAKMLFTG 176

Human   163 VIHLGCKPYLDSQRAACRC 181
            .:.|||:.|||||:.:|.|
  Fly   177 TLTLGCRSYLDSQQRSCYC 195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PLA2G12A	NP_110448.2	PLA2G12	24..189	CDD:399731	52/149 (35%)
GXIVsPLA2	NP_648815.1	Phospholip_A2_3	18..199	CDD:453050	52/149 (35%)