Protein Alignment TMX1 and CG11588

DIOPT Version :10

• Sequence 1: NP_110382.3
• Gene: TMX1 / 81542
• HGNCID: 15487
• Length: 280
• Species: Homo sapiens
• Sequence 2: NP_648522.1
• Gene: CG11588 / 39347
• FlyBaseID: FBgn0036221
• Length: 270
• Species: Drosophila melanogaster
• Alignment Length: 227
• Identity: 54/227 - (23%)
• Similarity: 99/227 - (43%)
• Gaps: 34/227 - (14%)

Human    34 ITDENWRELLEGDWMIEFYAPWCPACQNLQPEWESF------AEWGEDLEVNIAKVDVTEQPGLS 92
            |.:.||:|:|.|:|::...:...|:|    .:|::.      ...| .|:|::|..|::....|.
  Fly    54 IDEGNWKEVLTGEWLLLICSSHQPSC----GDWKAVLYQLASTSMG-CLDVDLAFGDLSTNFWLR 113

Human    93 GRFIITALPTIYHCKDGEFRRYQGPRTKKDFINFISDKEWKSIEPVSSWFGPGSVLMSSMSALFQ 157
            |||.......:||..||||||..........:|.:..:||..:.|:..|..|.|...:|...:.:
  Fly   114 GRFSAFREANVYHVVDGEFRRLSSSHDTNSILNLLLLREWSELPPMPFWLHPTSTWSTSAEFVLK 178

Human   158 LSMWIRTCHNYFIEDLGLPVWGSYTVFALATLF---SGLLLGLCMIFVAD--------CLCPSKR 211
            .::.::.     ::.||...|  .|...|..:|   :..:|.|.::...:        .|.|::.
  Fly   179 TAVDLKD-----LDILGRNAW--KTALILDLIFFIVTPYILWLTIMTTTENMMVNDEFKLGPTES 236

Human   212 RRPQPYPYPSKKLLSESAQP--LKKVEEEQEA 241
            ..|.|....||   .:|..|  |:|:.:.:|:
  Fly   237 SSPLPLKSISK---IKSTTPIFLQKLRQLRES 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TMX1	NP_110382.3	PDI_a_TMX	29..129	CDD:239292	28/100 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	218..280		7/26 (27%)
CG11588	NP_648522.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	51..148	CDD:469754	28/98 (29%)