Protein Alignment TMX1 and CG5554

DIOPT Version :10

• Sequence 1: NP_110382.3
• Gene: TMX1 / 81542
• HGNCID: 15487
• Length: 280
• Species: Homo sapiens
• Sequence 2: NP_001286784.1
• Gene: CG5554 / 37775
• FlyBaseID: FBgn0034914
• Length: 330
• Species: Drosophila melanogaster
• Alignment Length: 267
• Identity: 110/267 - (41%)
• Similarity: 163/267 - (61%)
• Gaps: 14/267 - (5%)

Human     7 LAVPLAVLVLLLWGAPWTHGRRSNVR------VITDENWRELLEGDWMIEFYAPWCPACQNLQPE 65
            :|...|.|:||...|..|...:|.::      .:.::||..:|:|:|||||:|||||||:||.|.
  Fly     8 VAATCAALLLLAATAQSTAAAQSGLQPGGKLIELDEDNWHLMLQGEWMIEFFAPWCPACKNLAPT 72

Human    66 WESFAEWGEDLEVNIAKVDVTEQPGLSGRFIITALPTIYHCKDGEFRRYQGPRTKKDFINFISDK 130
            ||.||...:|::|.:||:|||..|.|||||.:||||||||.||||||:|:|.|.....:.|:..:
  Fly    73 WERFARVAKDVQVQVAKIDVTTSPSLSGRFFVTALPTIYHVKDGEFRQYRGARDGDALLYFVKKQ 137

Human   131 EWKSIEPVSSWFGPGSVLMSSMSALFQLSMWIRTCHNYF-------IEDLGLPVWGSYTVFALAT 188
            :|:||||:|:|..|.:..||.:|..|:||..::.....|       .|:.|||.||||.:||:||
  Fly   138 QWQSIEPLSAWKKPDTTHMSVLSYFFKLSHTLKHTQKLFKDFNGRLQEEYGLPTWGSYALFAIAT 202

Human   189 LFSGLLLGLCMIFVADCLCPSKRRRPQPYPYPSKKLLSESAQPLKKVEEEQEADEEDVSEEEAES 253
            :|.|..|||.::.:.|.:.|.|:.:.|.:. .|:..|:|..:.|...|.|.:.|.|:..:|:.:|
  Fly   203 IFVGAALGLLLVCLVDFVYPPKKSQRQSFS-ESQDNLTEGLEDLATEEIEDDGDAEENDDEQRDS 266

Human   254 KEGTNKD 260
            .|...:|
  Fly   267 DEEEQED 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TMX1	NP_110382.3	PDI_a_TMX	29..129	CDD:239292	55/105 (52%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	218..280		12/43 (28%)
CG5554	NP_001286784.1	PDI_a_TMX	36..136	CDD:239292	54/99 (55%)