Protein Alignment TMX1 and prtp

DIOPT Version :10

• Sequence 1: NP_110382.3
• Gene: TMX1 / 81542
• HGNCID: 15487
• Length: 280
• Species: Homo sapiens
• Sequence 2: NP_572742.1
• Gene: prtp / 32124
• FlyBaseID: FBgn0030329
• Length: 416
• Species: Drosophila melanogaster
• Alignment Length: 275
• Identity: 71/275 - (25%)
• Similarity: 111/275 - (40%)
• Gaps: 53/275 - (19%)

Human    45 GDWMIEFYAPWCPACQNLQPEWESFAEW--GEDLEVNIAKVDVTEQPGLSGRFIITALPTIYHCK 107
            |:..::|:||||..|:.:||.||..||.  .::.:|.|||||.|:..||.....:|..||:...|
  Fly    54 GNVFVKFFAPWCGHCKRIQPLWEQLAEIMNVDNPKVIIAKVDCTKHQGLCATHQVTGYPTLRLFK 118

Human   108 DGEFR--RYQGPR---TKKDFINFISDKEWKSIEPVSSWFGP---GSVLMSSMSALFQLSMWIRT 164
            .||..  :::|.|   ...||||    ||..:  |..:..|.   ..|...::..:..|:.....
  Fly   119 LGEEESVKFKGTRDLPAITDFIN----KELSA--PAEADLGEVKREQVENLNIGKVVDLTEDTFA 177

Human   165 CH----NYFIEDLGLPVWGSYTVFALATLFSGL---LLGLCMIFVADCLCPSKRRRPQPYP---Y 219
            .|    |:|::...  .|.|:.. .||..:..|   |:....:.::...|...|...|.:.   |
  Fly   178 KHVSTGNHFVKFFA--PWCSHCQ-RLAPTWEDLAKELIKEPTVTISKIDCTQFRSICQDFEVKGY 239

Human   220 PS-------KKLLSESAQ----------------PLKKVEEEQEADEEDVSEEEAESKEGTNKDF 261
            |:       ||:...|..                ||:|...| ..||:.|.||.|..::...|..
  Fly   240 PTLLWIEDGKKIEKYSGARDLSTLKTYVEKMVGVPLEKTAGE-AGDEKVVIEEVAGEEDAAKKLT 303

Human   262 PQNAIRQRSLGPSLA 276
            ||....:.....::|
  Fly   304 PQQLTGEDEFDQAIA 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TMX1	NP_110382.3	PDI_a_TMX	29..129	CDD:239292	34/90 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	218..280		19/85 (22%)
prtp	NP_572742.1	PDI_a_ERp46	38..140	CDD:239303	31/85 (36%)
		PDI_a_ERp46	167..267	CDD:239303	18/102 (18%)
		PDI_a_ERp46	303..407	CDD:239303	3/16 (19%)