Protein Alignment CAMK2A and camk2a

DIOPT Version :10

• Sequence 1: NP_057065.2
• Gene: CAMK2A / 815
• HGNCID: 1460
• Length: 489
• Species: Homo sapiens
• Sequence 2: XP_068071964.1
• Gene: camk2a / 550436
• ZFINID: ZDB-GENE-051113-72
• Length: 493
• Species: Danio rerio
• Alignment Length: 491
• Identity: 458/491 - (93%)
• Similarity: 475/491 - (96%)
• Gaps: 4/491 - (0%)

Human     1 MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICR 65
            ||||||||||||||||||||||||||||||||||:|||||||||||||||.||||||:|||||||
Zfish     1 MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLSGQEYAAKIINTKKLSTRDHQKLDREARICR 65

Human    66 LLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 130
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish    66 LLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 130

Human   131 VVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVD 195
            ||||||||||||||||.|||||||||||||||||||||||||||||||||||||||||||||.||
Zfish   131 VVHRDLKPENLLLASKSKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKAVD 195

Human   196 LWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRI 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish   196 LWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRI 260

Human   261 TAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSGGKSGGNKKSD 325
            |||||||||||||||||||||||||||:|||||||||||||||||||||||||||||||.:||:|
Zfish   261 TAAEALKHPWISHRSTVASCMHRQETVECLKKFNARRKLKGAILTTMLATRNFSGGKSGVSKKTD 325

Human   326 GVK----KRKSSSSVQLMESSESTNTTIEDEDTKVRKQEIIKVTEQLIEAISNGDFESYTKMCDP 386
            |||    |.||||..||||||||||||||||||:|||||||||||||||||||||||||||||||
Zfish   326 GVKVGNQKSKSSSRTQLMESSESTNTTIEDEDTRVRKQEIIKVTEQLIEAISNGDFESYTKMCDP 390

Human   387 GMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYLDA 451
            .:|||||||||||||||||||||||||||:||||||||||||||||:|:|:|||||||||||||.
Zfish   391 SVTAFEPEALGNLVEGLDFHRFYFENLWSKNSKPVHTTILNPHIHLIGEEAACIAYIRITQYLDN 455

Human   452 GGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAPSVL 487
            .|:|.||||||||:|||:|||||||||||||:|:.:
Zfish   456 NGMPCTAQSEETRIWHRKDGKWQIVHFHRSGSPAAI 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAMK2A	NP_057065.2	STKc_CaMKII	11..302	CDD:270988	284/290 (98%)
		CaMKII_AD	357..484	CDD:285524	114/126 (90%)
camk2a	XP_068071964.1	STKc_CaMKII	11..302	CDD:270988	284/290 (98%)
		CaMKII_AD	361..488	CDD:285524	114/126 (90%)