DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment TAF15 and CG3732

DIOPT Version :9

Sequence 1:NP_631961.1 Gene:TAF15 / 8148 HGNCID:11547 Length:592 Species:Homo sapiens
Sequence 2:NP_611692.1 Gene:CG3732 / 37588 FlyBaseID:FBgn0034750 Length:282 Species:Drosophila melanogaster


Alignment Length:273 Identity:62/273 - (22%)
Similarity:81/273 - (29%) Gaps:63/273 - (23%)


- Green bases have known domain annotations that are detailed below.


Human   345 GFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRG 409
            |..|..|....|||:||:..|.::|||||..||:|:..|....:|.    |.|....|| .||.|
  Fly    11 GAAGSSGVASPGDWICPDYDCRHLNFARRLQCNKCDRDRDGSDKPE----RDRDRDRER-ERGNG 70

Human   410 GR-----------GGDRGGYGGDRSGGGYGGD-------------------RSSGGGYSGDRSGG 444
            ..           |.:.|....|:|.|.:..:                   ..:...:|......
  Fly    71 SSSSSSSSSKKKLGTEIGKAAADKSRGLFSAEDWQCSKCANVNWARRQTCNMCNAPKFSDVEERT 135

Human   445 GYGGDRSGGGYGGDRGGGYGGDRGGG------YGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGG 503
            |:     |||| .|||.....||...      :|..:...:|..|......|.......|.....
  Fly   136 GF-----GGGY-NDRGVVEYKDRQDSDSEYDEFGRRKKRKHGEHREDSKRPRRSSRDEQRNDEEE 194

Human   504 DRGGYGGD-----RGGYGGD-----------RGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGD 552
            |.....||     :....||           .|...||:.|.....|...........|.....|
  Fly   195 DEDDDEGDDEDLSKYDLWGDEEVTSTDVKSKEGTGNGDKERKRTSRDSTSSVSSSSSSSSSSSSD 259

Human   553 RSGGGYGGDRGGG 565
            .|.........||
  Fly   260 SSSSSSSSSSSGG 272

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TAF15NP_631961.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..237
G_path_suppress <1..124 CDD:318248
RRM 136..>315 CDD:330708
RRM_FUS_TAF15 232..317 CDD:240979
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 324..356 3/10 (30%)
zf-RanBP 354..384 CDD:279035 14/29 (48%)
RanBP2-type Zn finger 358..379 CDD:275375 11/20 (55%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 373..592 49/245 (20%)
21 X approximate tandem repeats of D-R-[S,G](0,3)-G-G-Y-G-G 407..575 38/211 (18%)
CG3732NP_611692.1 ZnF_RBZ 22..46 CDD:197784 13/23 (57%)
RanBP2-type Zn finger 24..45 CDD:275376 11/20 (55%)
zf-RanBP 100..129 CDD:279035 0/28 (0%)
RanBP2-type Zn finger 104..123 CDD:275376 0/18 (0%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1995
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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