Protein Alignment NPRL3 and nprl3

DIOPT Version :10

• Sequence 1: NP_001070818.1
• Gene: NPRL3 / 8131
• HGNCID: 14124
• Length: 569
• Species: Homo sapiens
• Sequence 2: XP_073798710.1
• Gene: nprl3 / 564989
• ZFINID: ZDB-GENE-030131-1348
• Length: 624
• Species: Danio rerio
• Alignment Length: 584
• Identity: 447/584 - (76%)
• Similarity: 497/584 - (85%)
• Gaps: 21/584 - (3%)

Human     3 DNTSPISVILVSSGSRGNKLLFRYPFQRSQEHPASQTSKPRSRYAASNTGDHADEQDGDSR---- 63
            :.||||||||||||||||||||||||||:.|:.:|.|||.||.|..:.:||..::||||||
Zfish    39 EKTSPISVILVSSGSRGNKLLFRYPFQRASENTSSATSKQRSPYVLNTSGDSTEDQDGDSREQSP 103

Human    64 ---------FSDVILATILATKSEMCGQKFELKIDNVRFVGHPTLLQ--HALGQISKTDPSPKRE 117
                     |||:||||||||||:|||:|||||||||||||||||||  |.: |.||||||||||
Zfish   104 LTDEQLVSGFSDIILATILATKSDMCGKKFELKIDNVRFVGHPTLLQPPHTI-QASKTDPSPKRE 167

Human   118 APTMILFNVVFALRANADPSVINCLHNLSRRIATVLQHEERRCQYLTREAKLILALQDEVSAMAD 182
            .||||||:||||||||||.|||:|:||||||||..|||||||||||||||||:|.:||||:.:.|
Zfish   168 LPTMILFSVVFALRANADASVISCMHNLSRRIAIALQHEERRCQYLTREAKLMLVMQDEVTTITD 232

Human   183 GNEGPQSPFHHILPKCKLARDLKEAYDSLCTSGVVRLHINSWLEVSFCLPHKIHYAASSLIPPEA 247
            .:..|||||..||||||||||||||||||||:||||||||:|||||||||||||......||.||
Zfish   233 SDGSPQSPFRQILPKCKLARDLKEAYDSLCTTGVVRLHINNWLEVSFCLPHKIHRVGGKHIPLEA 297

Human   248 IERSLKAIRPYHALLLLSDEKSLLGELPIDCSPALVRVIKTTSAVKNLQQLAQDADLALLQVFQL 312
            :||||||||||||||||.:||.||.:||:||||||||:|||.|||||||||||||||||||:||:
Zfish   298 LERSLKAIRPYHALLLLENEKVLLAQLPLDCSPALVRLIKTCSAVKNLQQLAQDADLALLQIFQI 362

Human   313 AAHLVYWGKAIIIYPLCENNVYMLSPNASVCL-----YSPLAEQFSHQFPSHDLPSVLAKFSLPV 372
            ||||||||||||||||||||||||||:|::|:     ||||||.|:.|||.|||||:||||||||
Zfish   363 AAHLVYWGKAIIIYPLCENNVYMLSPHANICISSPSSYSPLAEHFAVQFPGHDLPSMLAKFSLPV 427

Human   373 SLSEFRNPLAPAVQETQLIQMVVWMLQRRLLIQLHTYVCLMASPSEEEPRPREDDVPFTARVGGR 437
            |||||||||...|.|..||||||||||.|||.||||||||:..|:||||..|::::|...||.||
Zfish   428 SLSEFRNPLDAPVHEAHLIQMVVWMLQHRLLFQLHTYVCLLVPPNEEEPGLRDEELPIVTRVTGR 492

Human   438 SLSTPNALSFGSPTSSDDMTLTSPSMDNSSAELLPSGDSPLNQRMTENLLASLSEHERAAILSVP 502
            |||||:|||||||||||||||||||||||||||...||||||:||||.|||||:||||.|||.||
Zfish   493 SLSTPSALSFGSPTSSDDMTLTSPSMDNSSAELQTGGDSPLNKRMTETLLASLTEHERQAILRVP 557

Human   503 AAQNPEDLRMFARLLHYFRGRHHLEEIMYNENTRRSQLLMLFDKFRSVLVVTTHEDPVIAVFQA 566
            |||||||||:||||||||||.|||||||||||.|||||..||||||||||:|.||||:|::||:
Zfish   558 AAQNPEDLRLFARLLHYFRGHHHLEEIMYNENLRRSQLKTLFDKFRSVLVITNHEDPIISLFQS 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPRL3	NP_001070818.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	27..60		15/32 (47%)
		NPR3	64..416	CDD:451662	285/358 (80%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	416..477		45/60 (75%)
nprl3	XP_073798710.1	None