Protein Alignment NPRL3 and Nprl3

DIOPT Version :10

• Sequence 1: NP_001070818.1
• Gene: NPRL3 / 8131
• HGNCID: 14124
• Length: 569
• Species: Homo sapiens
• Sequence 2: NP_001271288.1
• Gene: Nprl3 / 17168
• MGIID: 109258
• Length: 582
• Species: Mus musculus
• Alignment Length: 581
• Identity: 547/581 - (94%)
• Similarity: 558/581 - (96%)
• Gaps: 13/581 - (2%)

Human     1 MRDNTSPISVILVSSGSRGNKLLFRYPFQRSQEHPASQTSKPRSRYAASNTGDHADEQDGDSR-- 63
            |.|||||||||||||||||||||||||||||||||||||:|||||||.:|||:|||:|||||.
Mouse     1 MGDNTSPISVILVSSGSRGNKLLFRYPFQRSQEHPASQTNKPRSRYAVNNTGEHADDQDGDSSKP 65

Human    64 -----------FSDVILATILATKSEMCGQKFELKIDNVRFVGHPTLLQHALGQISKTDPSPKRE 117
                       |||||||||||||||||||||||||||||||||||||||||||:||||||||||
Mouse    66 CPPTDEQLVAGFSDVILATILATKSEMCGQKFELKIDNVRFVGHPTLLQHALGQVSKTDPSPKRE 130

Human   118 APTMILFNVVFALRANADPSVINCLHNLSRRIATVLQHEERRCQYLTREAKLILALQDEVSAMAD 182
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   131 APTMILFNVVFALRANADPSVINCLHNLSRRIATVLQHEERRCQYLTREAKLILALQDEVSAMAD 195

Human   183 GNEGPQSPFHHILPKCKLARDLKEAYDSLCTSGVVRLHINSWLEVSFCLPHKIHYAASSLIPPEA 247
            .||||||||.|||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   196 ANEGPQSPFQHILPKCKLARDLKEAYDSLCTSGVVRLHINSWLEVSFCLPHKIHYAASSLIPPEA 260

Human   248 IERSLKAIRPYHALLLLSDEKSLLGELPIDCSPALVRVIKTTSAVKNLQQLAQDADLALLQVFQL 312
            ||||||||||||||||||||||||.||||||||||||||||||||||||||||||||||||||||
Mouse   261 IERSLKAIRPYHALLLLSDEKSLLSELPIDCSPALVRVIKTTSAVKNLQQLAQDADLALLQVFQL 325

Human   313 AAHLVYWGKAIIIYPLCENNVYMLSPNASVCLYSPLAEQFSHQFPSHDLPSVLAKFSLPVSLSEF 377
            ||||||||||:|||||||||||::|||||||||||||||||.|||||||||||||||||||||||
Mouse   326 AAHLVYWGKAVIIYPLCENNVYVMSPNASVCLYSPLAEQFSRQFPSHDLPSVLAKFSLPVSLSEF 390

Human   378 RNPLAPAVQETQLIQMVVWMLQRRLLIQLHTYVCLMASPSEEEPRPREDDVPFTARVGGRSLSTP 442
            |:||||..|||||||||||||||||||||||||||||||||||||.|||||||||||||||||||
Mouse   391 RSPLAPPAQETQLIQMVVWMLQRRLLIQLHTYVCLMASPSEEEPRLREDDVPFTARVGGRSLSTP 455

Human   443 NALSFGSPTSSDDMTLTSPSMDNSSAELLPSGDSPLNQRMTENLLASLSEHERAAILSVPAAQNP 507
            |||||||||||||||||||||||||||||||||||||:|||||||||||||||||||:|||||||
Mouse   456 NALSFGSPTSSDDMTLTSPSMDNSSAELLPSGDSPLNKRMTENLLASLSEHERAAILNVPAAQNP 520

Human   508 EDLRMFARLLHYFRGRHHLEEIMYNENTRRSQLLMLFDKFRSVLVVTTHEDPVIAVFQALL 568
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   521 EDLRMFARLLHYFRGRHHLEEIMYNENTRRSQLLMLFDKFRSVLVVTTHEDPVIAVFQALL 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPRL3	NP_001070818.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	27..60		27/32 (84%)
		NPR3	64..416	CDD:451662	340/351 (97%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	416..477		59/60 (98%)
Nprl3	NP_001271288.1	NPR3	76..429	CDD:451662	340/352 (97%)