Protein Alignment NPRL3 and nprl3

DIOPT Version :10

• Sequence 1: NP_001070818.1
• Gene: NPRL3 / 8131
• HGNCID: 14124
• Length: 569
• Species: Homo sapiens
• Sequence 2: XP_012825411.1
• Gene: nprl3 / 100124838
• XenbaseID: XB-GENE-5818915
• Length: 580
• Species: Xenopus tropicalis
• Alignment Length: 582
• Identity: 475/582 - (81%)
• Similarity: 522/582 - (89%)
• Gaps: 15/582 - (2%)

Human     1 MRDNTSPISVILVSSGSRGNKLLFRYPFQRSQEHPASQTSKPRSRYAASNTGDHADEQDGDSR-- 63
            |.:|||||||||||||||||||||||||||:.|...|:|..|||.||..||||::|:.||||:
 Frog     1 MGENTSPISVILVSSGSRGNKLLFRYPFQRNHEPQLSKTINPRSCYALPNTGDNSDDPDGDSKEP 65

Human    64 -----------FSDVILATILATKSEMCGQKFELKIDNVRFVGHPTLLQHALGQISKTDPSPKRE 117
                       ||||||||||||||:|||:|||||||||||||||||||||  |:||||||||||
 Frog    66 CPLTDEQLVEGFSDVILATILATKSDMCGKKFELKIDNVRFVGHPTLLQHA--QVSKTDPSPKRE 128

Human   118 APTMILFNVVFALRANADPSVINCLHNLSRRIATVLQHEERRCQYLTREAKLILALQDEVSAMAD 182
            |||||||||||||||||||||||||||||||||.|||||||||||||||||||||:||||:||::
 Frog   129 APTMILFNVVFALRANADPSVINCLHNLSRRIAIVLQHEERRCQYLTREAKLILAIQDEVTAMSE 193

Human   183 GNEGPQSPFHHILPKCKLARDLKEAYDSLCTSGVVRLHINSWLEVSFCLPHKIHYAASSLIPPEA 247
            .|.||||||||||||||||||||||||||||:||||||||:|||||||||||||...::.|||:|
 Frog   194 TNGGPQSPFHHILPKCKLARDLKEAYDSLCTTGVVRLHINNWLEVSFCLPHKIHCVGTNFIPPDA 258

Human   248 IERSLKAIRPYHALLLLSDEKSLLGELPIDCSPALVRVIKTTSAVKNLQQLAQDADLALLQVFQL 312
            ||:|||:||||||||||.|||:||.:||:||||||||:||:.|||||||||||||||||||||||
 Frog   259 IEKSLKSIRPYHALLLLKDEKNLLNDLPLDCSPALVRIIKSASAVKNLQQLAQDADLALLQVFQL 323

Human   313 AAHLVYWGKAIIIYPLCENNVYMLSPNASVCLYSPLAEQFSHQFPSHDLPSVLAKFSLPVSLSEF 377
            ||||||||||||||||||||||||||||:|.|||.||||||||||:|||||||:||||||||||.
 Frog   324 AAHLVYWGKAIIIYPLCENNVYMLSPNANVGLYSSLAEQFSHQFPAHDLPSVLSKFSLPVSLSEL 388

Human   378 RNPLAPAVQETQLIQMVVWMLQRRLLIQLHTYVCLMASPSEEEPRPREDDVPFTARVGGRSLSTP 442
            :|||:|..||..|||||:||||.|||||:||||||:..|:|:....:::|.||.|||||||||||
 Frog   389 KNPLSPPGQEPHLIQMVIWMLQHRLLIQIHTYVCLLVPPNEDVASTKDEDTPFAARVGGRSLSTP 453

Human   443 NALSFGSPTSSDDMTLTSPSMDNSSAELLPSGDSPLNQRMTENLLASLSEHERAAILSVPAAQNP 507
            ||||||||||||||||||||||||||||||..|||:|:|.|||||||||:|||.||||:|||||.
 Frog   454 NALSFGSPTSSDDMTLTSPSMDNSSAELLPGADSPVNKRATENLLASLSQHEREAILSIPAAQNQ 518

Human   508 EDLRMFARLLHYFRGRHHLEEIMYNENTRRSQLLMLFDKFRSVLVVTTHEDPVIAVFQALLP 569
            |||:|||||||||||||||||||||||.|||||||||||||||||||.||||||:|||::.|
 Frog   519 EDLKMFARLLHYFRGRHHLEEIMYNENMRRSQLLMLFDKFRSVLVVTNHEDPVISVFQSVFP 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPRL3	NP_001070818.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	27..60		17/32 (53%)
		NPR3	64..416	CDD:451662	303/351 (86%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	416..477		47/60 (78%)
nprl3	XP_012825411.1	NPR3	76..428	CDD:451662	303/353 (86%)