| Sequence 1: | NP_004634.1 | Gene: | PABPN1 / 8106 | HGNCID: | 8565 | Length: | 306 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001285330.1 | Gene: | eIF4H1 / 49809 | FlyBaseID: | FBgn0262734 | Length: | 388 | Species: | Drosophila melanogaster |
| Alignment Length: | 161 | Identity: | 37/161 - (22%) |
|---|---|---|---|
| Similarity: | 60/161 - (37%) | Gaps: | 46/161 - (28%) |
- Green bases have known domain annotations that are detailed below.
|
Human 175 YVGNVDYGATAEELEAHFHGCGSVNRVTILCDKFSGHPKGFAYIEFSDKESVRTSLALD-----E 234
Human 235 SLFRGRQIKVIPKRTN-RP---------GISTTD--------RGFPRARYRAR------------ 269
Human 270 -------TTNYNSSRSRF---YSGFNSRPRG 290 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| PABPN1 | NP_004634.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..115 | ||
| Interaction with SKIP. /evidence=ECO:0000269|PubMed:11371506 | 2..145 | ||||
| GCG-encoded polyalanine repeat | 2..7 | ||||
| Stimulates PAPOLA. /evidence=ECO:0000250 | 119..147 | ||||
| Necessary for homooligomerization | 155..306 | 37/161 (23%) | |||
| RRM_II_PABPN1 | 173..248 | CDD:409966 | 18/77 (23%) | ||
| Interaction with PAPOLA. /evidence=ECO:0000250 | 286..306 | 3/5 (60%) | |||
| eIF4H1 | NP_001285330.1 | RRM_eIF4H | 24..110 | CDD:409835 | 18/78 (23%) |
| Blue background indicates that the domain is not in the aligned region. | |||||