| Sequence 1: | NP_004634.1 | Gene: | PABPN1 / 8106 | HGNCID: | 8565 | Length: | 306 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_476902.1 | Gene: | Pabp2 / 35788 | FlyBaseID: | FBgn0005648 | Length: | 224 | Species: | Drosophila melanogaster |
| Alignment Length: | 218 | Identity: | 128/218 - (58%) |
|---|---|---|---|
| Similarity: | 156/218 - (71%) | Gaps: | 20/218 - (9%) |
- Green bases have known domain annotations that are detailed below.
|
Human 94 GSQEEE-----EEPGLVEGDPGDGAIEDPELEAIKARVREMEEEAEKLKELQNEVEKQMNMSPPP 153
Human 154 GNAGPVIMSIEEKMEADARSIYVGNVDYGATAEELEAHFHGCGSVNRVTILCDKFSGHPKGFAYI 218
Human 219 EFSDKESVRTSLALDESLFRGRQIKVIPKRTNRPGISTTDRGFPRARYRARTTNYNSSRSRFYSG 283
Human 284 FNSRPRGRVYRGRARATSWYSPY 306 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| PABPN1 | NP_004634.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..115 | 7/25 (28%) | |
| Interaction with SKIP. /evidence=ECO:0000269|PubMed:11371506 | 2..145 | 30/55 (55%) | |||
| GCG-encoded polyalanine repeat | 2..7 | ||||
| RRM | 113..>289 | CDD:223796 | 112/175 (64%) | ||
| Stimulates PAPOLA. /evidence=ECO:0000250 | 119..147 | 21/27 (78%) | |||
| Necessary for homooligomerization | 155..306 | 92/150 (61%) | |||
| RRM_II_PABPN1 | 173..248 | CDD:409966 | 57/74 (77%) | ||
| Interaction with PAPOLA. /evidence=ECO:0000250 | 286..306 | 7/19 (37%) | |||
| Pabp2 | NP_476902.1 | RRM | <43..>172 | CDD:223796 | 91/129 (71%) |
| RRM_II_PABPN1 | 97..172 | CDD:240994 | 57/74 (77%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165150027 | |
| Domainoid | 1 | 1.000 | 123 | 1.000 | Domainoid score | I5604 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG4209 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H3412 | |
| Inparanoid | 1 | 1.050 | 230 | 1.000 | Inparanoid score | I3448 |
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S1069 |
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D1412946at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0001228 | |
| OrthoInspector | 1 | 1.000 | - | - | oto91785 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_101686 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR23236 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R4120 |
| SonicParanoid | 1 | 1.000 | - | - | X689 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 16 | 15.740 | |||||