Protein Alignment EGFL8 and egfl7

DIOPT Version :9

• Sequence 1: NP_085155.1
• Gene: EGFL8 / 80864
• HGNCID: 13944
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_001035475.1
• Gene: egfl7 / 678640
• ZFINID: ZDB-GENE-040429-2
• Length: 277
• Species: Danio rerio
• Alignment Length: 257
• Identity: 96/257 - (37%)
• Similarity: 130/257 - (50%)
• Gaps: 47/257 - (18%)

Human    51 ESYSQPVYKPYLTLCAGRRICSTYRTMYRVMWREVRREVQ--QTHAVCCQGWKKRHPGALTC-EA 112
            ||:.|||:|||:|:|...|:||||:|:|:|.:|:|.|...  |.:..||.||::.|  :..| :|
Zfish    45 ESFLQPVHKPYITMCQNHRMCSTYKTIYKVSYRQVSRAAPNLQIYPECCPGWRRMH--SHNCNQA 107

Human   113 ICAKPCLNGGVCVRPDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCPHDLVLG 177
            :|.:.|.|||.||||:.|.|..||.|:.|.:|||||:.:.: ||..|.||.|||.|.|.....|.
Zfish   108 VCEQSCANGGSCVRPNHCACLRGWTGRFCQIDVDECKEAQS-CSQKCVNTLGSFQCVCEEGFSLD 171

Human   178 VDGRTCMEGSPEPPTSASILSVAVREAEKDERALKQEIHELRGRLERLEQWAGQAGAWVRAVLPV 242
            .|..||.:.......:...|.:.....|        |:..|:.|:|.|||......|....:||
Zfish   172 EDKVTCSKNPASSRNTGGGLGLVENVTE--------EVQILKNRVELLEQKLEMVLAPFTTLLP- 227

Human   243 PPEELQPEQVAELWGRG--------------------DRIESLSDQVLLLEERLGACSCEDN 284
                        |.|.|                    |||||||:||..||||:|||.|::|
Zfish   228 ------------LDGAGDTNSFLSERTNFLSHSLQQLDRIESLSEQVGFLEERIGACGCQEN 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EGFL8	NP_085155.1	EMI	37..101	CDD:311482	25/51 (49%)
		vWFA	<119..182	CDD:320736	30/62 (48%)
		FXa_inhibition	155..183	CDD:317114	12/27 (44%)
egfl7	NP_001035475.1	EMI	29..97	CDD:284877	25/51 (49%)
		EGF_CA	139..169	CDD:214542	15/30 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG43856
OrthoDB	1	1.010	-	-		D315399at7742
OrthoFinder	1	1.000	-	-		FOG0001719
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_109468
Panther	1	1.100	-	-	O	PTHR14949
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4227
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.930