Protein Alignment EGFL8 and Egfl8

DIOPT Version :9

• Sequence 1: NP_085155.1
• Gene: EGFL8 / 80864
• HGNCID: 13944
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_001004070.1
• Gene: Egfl8 / 406166
• RGDID: 1549706
• Length: 291
• Species: Rattus norvegicus
• Alignment Length: 287
• Identity: 232/287 - (80%)
• Similarity: 249/287 - (86%)
• Gaps: 1/287 - (0%)

Human     5 AELCTLLGGFSFLLLLIPGEGAKGGSLRESQGVCSKQTLVVPLHYNESYSQPVYKPYLTLCAGRR 69
            |..|..|.||||||:|:. ||||||..:||.||||||||:|||.||||||||||:||||||||||
  Rat     5 AGCCIFLRGFSFLLVLMT-EGAKGGPFKESLGVCSKQTLLVPLRYNESYSQPVYRPYLTLCAGRR 68

Human    70 ICSTYRTMYRVMWREVRREVQQTHAVCCQGWKKRHPGALTCEAICAKPCLNGGVCVRPDQCECAP 134
            |||||||.|||.||||||||||||.||||||||.|||||||||||:|||||||||..|||||||.
  Rat    69 ICSTYRTTYRVAWREVRREVQQTHVVCCQGWKKPHPGALTCEAICSKPCLNGGVCAGPDQCECAS 133

Human   135 GWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTCMEGSPEPPTSASILSV 199
            ||.||||||||||||||:|||||.|.||.|||||.||:.||||.|||.|..|.||..|||.||||
  Rat   134 GWAGKHCHVDVDECRTSLTLCSHGCLNTLGSFTCSCPNPLVLGPDGRACAGGPPESSTSAGILSV 198

Human   200 AVREAEKDERALKQEIHELRGRLERLEQWAGQAGAWVRAVLPVPPEELQPEQVAELWGRGDRIES 264
            |||||:.:|.||::|:.|||||||||||||.||||||||||||.||:|:||||||||||||||||
  Rat   199 AVREADSEEHALRREVAELRGRLERLEQWATQAGAWVRAVLPVAPEDLRPEQVAELWGRGDRIES 263

Human   265 LSDQVLLLEERLGACSCEDNSLGLGVN 291
            |||||||||||||||||||||||.|::
  Rat   264 LSDQVLLLEERLGACSCEDNSLGPGLH 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EGFL8	NP_085155.1	EMI	37..101	CDD:311482	57/63 (90%)
		vWFA	<119..182	CDD:320736	50/62 (81%)
		FXa_inhibition	155..183	CDD:317114	20/27 (74%)
Egfl8	NP_001004070.1	EMI	36..100	CDD:400092	57/63 (90%)
		vWFA	<108..181	CDD:412136	59/72 (82%)
		EGF_CA	143..>170	CDD:214542	21/26 (81%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83690261
Domainoid	1	1.000	176	1.000	Domainoid score	I27694
eggNOG	0	0.000	Not matched by this tool.
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H36473
Inparanoid	1	1.050	491	1.000	Inparanoid score	I11921
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG43856
OrthoDB	1	1.010	-	-		D152127at9347
OrthoFinder	1	1.000	-	-		FOG0001719
OrthoInspector	1	1.000	-	-		oto140209
orthoMCL	1	0.900	-	-		OOG6_109468
Panther	1	1.100	-	-	LDO	PTHR14949
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4227
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	16.370