Protein Alignment CALM3 and Mlc2

DIOPT Version :10

• Sequence 1: NP_005175.2
• Gene: CALM3 / 808
• HGNCID: 1449
• Length: 149
• Species: Homo sapiens
• Sequence 2: NP_524586.1
• Gene: Mlc2 / 43587
• FlyBaseID: FBgn0002773
• Length: 222
• Species: Drosophila melanogaster
• Alignment Length: 147
• Identity: 52/147 - (35%)
• Similarity: 81/147 - (55%)
• Gaps: 9/147 - (6%)

Human     6 TEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFL 70
            :::|||||||||.|.|.|.||.|...:|.....|:|:...:.||..|:.|    .:|.|:|.:.|
  Fly    73 SQKQIAEFKEAFQLMDADKDGIIGKNDLRAAFDSVGKIANDKELDAMLGE----ASGPINFTQLL 133

Human    71 TMMARKMKDT---DSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADID 132
            |:.|.:|..:   |.:|.:..||:.||.|  |.|...:.|.::.|.|:|.|.:|||:...:..||
  Fly   134 TLFANRMATSGANDEDEVVIAAFKTFDND--GLIDGDKFREMLMNFGDKFTMKEVDDAYDQMVID 196

Human   133 GDGQVNYEEFVQMMTAK 149
            ...|::....::|:|.|
  Fly   197 DKNQIDTAALIEMLTGK 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CALM3	NP_005175.2	PTZ00184	1..149	CDD:185504	51/145 (35%)
		Necessary and sufficient for interaction with PCP4. /evidence=ECO:0000269|PubMed:27876793	77..149		23/74 (31%)
Mlc2	NP_524586.1	PTZ00184	73..213	CDD:185504	51/145 (35%)