Protein Alignment CALM3 and Mlc1

DIOPT Version :10

• Sequence 1: NP_005175.2
• Gene: CALM3 / 808
• HGNCID: 1449
• Length: 149
• Species: Homo sapiens
• Sequence 2: NP_476639.1
• Gene: Mlc1 / 43323
• FlyBaseID: FBgn0002772
• Length: 155
• Species: Drosophila melanogaster
• Alignment Length: 159
• Identity: 47/159 - (29%)
• Similarity: 77/159 - (48%)
• Gaps: 25/159 - (15%)

Human     1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT-- 63
            ||| :.:.::...:..|.:....|:| |...:||..:|:|..|||.|.::.:        .||
  Fly     1 MAD-VPKREVENVEFVFEVMGSPGEG-IDAVDLGDALRALNLNPTLALIEKL--------GGTKK 55

Human    64 -----IDFPEFLTM--MARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEE 121
                 |...|||.:  ..:|.|:....|:..|..:::||:.||.:..|||:|.:..|||.|.||:
  Fly    56 RNEKKIKLDEFLPIYSQVKKEKEQGCYEDFIECLKLYDKEENGTMLLAELQHALLALGESLDDEQ 120

Human   122 VDEMIREADI----DGDGQVNYEEFVQMM 146
            |:.:.  ||.    |.:|.:.|..|:..|
  Fly   121 VETLF--ADCMDPEDDEGFIPYSPFLARM 147

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CALM3	NP_005175.2	PTZ00184	1..149	CDD:185504	47/159 (30%)
		Necessary and sufficient for interaction with PCP4. /evidence=ECO:0000269|PubMed:27876793	77..149		25/74 (34%)
Mlc1	NP_476639.1	PTZ00184	1..150	CDD:185504	47/159 (30%)